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    vpr Vpr [ Human immunodeficiency virus 1 ]

    Gene ID: 155807, updated on 6-Oct-2023

    Summary

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    Gene symbol
    vpr
    Gene description
    Vpr
    Locus tag
    HIV1gp4
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Human immunodeficiency virus 1
    Lineage
    Viruses; Retro-transcribing viruses; Retroviridae; Orthoretrovirinae; Lentivirus; Primate lentivirus group
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    Genomic context

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    Sequence:
    NC_001802.1 (5105..5396)

    NC_001802.1Genomic Context describing neighboring genes Neighboring gene Gag-Pol Neighboring gene Pr55(Gag) Neighboring gene Vif Neighboring gene Tat Neighboring gene Rev Neighboring gene Vpu Neighboring gene Envelope surface glycoprotein gp160, precursor Neighboring gene Asp

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001802.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Tubular-specific expression of HIV protein Vpr leads to severe tubulointerstitial damage accompanied by progressive fibrosis and cystic development. Chen Y, et al. Kidney Int, 2023 Mar. PMID 36565808, Free PMC Article
    2. Genetic Analysis of HIV-1 vpr Sequences from HIV-Infected Older Patients on Long-Term Antiretroviral Therapy. Love M, et al. Curr HIV Res, 2022. PMID 35792120
    3. HIV-1 Vpr Induces Widespread Transcriptomic Changes in CD4(+) T Cells Early Postinfection. Bauby H, et al. mBio, 2021 Jun 29. PMID 34154423, Free PMC Article
    4. Viral protein R polymorphisms in the pathogenesis of HIV-associated acute ischaemic stroke: a case-control study. McMullen K, et al. J Neurovirol, 2021 Feb. PMID 33462790
    5. HIV-1 Vpr antagonizes innate immune activation by targeting karyopherin-mediated NF-κB/IRF3 nuclear transport. Khan H, et al. Elife, 2020 Dec 10. PMID 33300875, Free PMC Article

    See all (449) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Viral protein R (Vpr)-induced neuroinflammation and its potential contribution to neuronal dysfunction: a scoping review.
      Title: Viral protein R (Vpr)-induced neuroinflammation and its potential contribution to neuronal dysfunction: a scoping review.
    2. HIV-1 Vpr Induces Degradation of Gelsolin, a Myeloid Cell-Specific Host Factor That Reduces Viral Infectivity by Inhibiting the Expression and Packaging of the HIV-1 Env Glycoprotein.
      Title: HIV-1 Vpr Induces Degradation of Gelsolin, a Myeloid Cell-Specific Host Factor That Reduces Viral Infectivity by Inhibiting the Expression and Packaging of the HIV-1 Env Glycoprotein.
    3. Tubular-specific expression of HIV protein Vpr leads to severe tubulointerstitial damage accompanied by progressive fibrosis and cystic development.
      Title: Tubular-specific expression of HIV protein Vpr leads to severe tubulointerstitial damage accompanied by progressive fibrosis and cystic development.
    4. Genetic Analysis of HIV-1 vpr Sequences from HIV-Infected Older Patients on Long-Term Antiretroviral Therapy.
      Title: Genetic Analysis of HIV-1 vpr Sequences from HIV-Infected Older Patients on Long-Term Antiretroviral Therapy.
    5. Structure of HIV-1 Vpr in complex with the human nucleotide excision repair protein hHR23A.
      Title: Structure of HIV-1 Vpr in complex with the human nucleotide excision repair protein hHR23A.
    6. Viral protein R polymorphisms in the pathogenesis of HIV-associated acute ischaemic stroke: a case-control study.
      Title: Viral protein R polymorphisms in the pathogenesis of HIV-associated acute ischaemic stroke: a case-control study.
    7. HIV-1 Vpr Induces Widespread Transcriptomic Changes in CD4(+) T Cells Early Postinfection.
      Title: HIV-1 Vpr Induces Widespread Transcriptomic Changes in CD4(+) T Cells Early Postinfection.
    8. The SMC5/6 complex compacts and silences unintegrated HIV-1 DNA and is antagonized by Vpr.
      Title: The SMC5/6 complex compacts and silences unintegrated HIV-1 DNA and is antagonized by Vpr.
    9. HIV reprograms host m(6)Am RNA methylome by viral Vpr protein-mediated degradation of PCIF1.
      Title: HIV reprograms host m(6)Am RNA methylome by viral Vpr protein-mediated degradation of PCIF1.
    10. Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.
      Title: Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.
    Submit: New GeneRIF Correction See all GeneRIFs (188)

    HIV-1 interactions

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    Protein interactions

    Protein Gene Interaction Pubs
    cholesterol transporter ABCA5 ABCA5 interacts with PubMed
    ATP-binding cassette sub-family D member 3 isoform a ABCD3 interacts with PubMed
    3-ketoacyl-CoA thiolase, mitochondrial ACAA2 enhances PubMed
    acetyl-CoA acetyltransferase, mitochondrial isoform b precursor ACAT1 downregulates PubMed
    Golgi resident protein GCP60 ACBD3 downregulates PubMed
    acyl-CoA-binding domain-containing protein 5 isoform 1 ACBD5 interacts with PubMed
    long-chain-fatty-acid--CoA ligase 4 isoform 1 ACSL4 upregulates PubMed
    actin, aortic smooth muscle isoform 1 ACTA2 downregulates PubMed
    actin, cytoplasmic 1 ACTB downregulates PubMed
    beta-actin-like protein 2 ACTBL2 downregulates PubMed
    actin, cytoplasmic 2 ACTG1 downregulates PubMed
    ACTG1 enhances polymerization of PubMed
    alpha-actinin-1 isoform a ACTN1 upregulates PubMed
    alpha-actinin-4 isoform 1 ACTN4 upregulates PubMed
    alkyldihydroxyacetonephosphate synthase, peroxisomal precursor AGPS interacts with PubMed
    aryl hydrocarbon receptor AHR regulated by PubMed
    AHR cooperates with PubMed
    single-stranded DNA cytosine deaminase isoform 1 AICDA co-localizes with PubMed
    AICDA inhibits PubMed
    AICDA interacts with PubMed
    apoptosis-inducing factor 1, mitochondrial isoform AIF precursor AIFM1 downregulates PubMed
    AIFM1 interacts with PubMed
    adenylate kinase 2, mitochondrial isoform a AK2 downregulates PubMed
    RAC-alpha serine/threonine-protein kinase AKT1 involves PubMed
    AKT1 involves PubMed
    AKT1 decreases phosphorylation of PubMed
    AKT1 inhibits PubMed
    RAC-beta serine/threonine-protein kinase isoform 1 AKT2 regulated by PubMed
    AKT2 involves PubMed
    AKT2 involves PubMed
    AKT2 decreases phosphorylation of PubMed
    AKT2 inhibits PubMed
    RAC-gamma serine/threonine-protein kinase isoform 1 AKT3 regulated by PubMed
    AKT3 inhibits PubMed
    fructose-bisphosphate aldolase A isoform 1 ALDOA downregulates PubMed
    fructose-bisphosphate aldolase C ALDOC downregulates PubMed
    ankyrin repeat and KH domain-containing protein 1 isoform 1 ANKHD1 interacts with PubMed
    ankyrin repeat domain-containing protein 13A ANKRD13A interacts with PubMed
    ankyrin repeat domain-containing protein 17 isoform a ANKRD17 interacts with PubMed
    anillin isoform 1 ANLN upregulates PubMed
    annexin A3 ANXA3 downregulates PubMed
    DNA dC->dU-editing enzyme APOBEC-3A isoform b APOBEC3A upregulates PubMed
    DNA dC->dU-editing enzyme APOBEC-3C APOBEC3C upregulates PubMed
    DNA dC->dU-editing enzyme APOBEC-3G isoform 1 APOBEC3G induces ubiquitination of PubMed
    APOBEC3G degrades PubMed
    APOBEC3G upregulates PubMed
    apolipoprotein E isoform b precursor APOE upregulates PubMed
    arginase-2, mitochondrial precursor ARG2 downregulates PubMed
    rho GDP-dissociation inhibitor 1 isoform a ARHGDIA upregulates PubMed
    rho GDP-dissociation inhibitor 2 ARHGDIB modulates PubMed
    acid ceramidase isoform b ASAH1 upregulates PubMed
    cyclic AMP-dependent transcription factor ATF-1 isoform c ATF1 activates PubMed
    ATF1 activates PubMed
    serine-protein kinase ATM isoform a ATM activates PubMed
    ATP synthase subunit alpha, mitochondrial isoform a precursor ATP5F1A downregulates PubMed
    ATP synthase subunit beta, mitochondrial precursor ATP5F1B downregulates PubMed
    ATP synthase subunit delta, mitochondrial precursor ATP5F1D downregulates PubMed
    ATP synthase F(0) complex subunit B1, mitochondrial precursor ATP5PB downregulates PubMed
    V-type proton ATPase subunit B, brain isoform ATP6V1B2 upregulates PubMed
    serine/threonine-protein kinase ATR isoform 1 ATR activates PubMed
    ATR activates PubMed
    ATR interacts with PubMed
    ATR activates PubMed
    ATR activates PubMed
    ATR interacts with PubMed
    ATR activates PubMed
    ATR interacts with PubMed
    aurora kinase A isoform 1 AURKA upregulates PubMed
    aurora kinase B isoform 1 AURKB upregulates PubMed
    AURKB downregulates PubMed
    tyrosine-protein kinase receptor UFO isoform 3 AXL upregulates PubMed
    apoptosis regulator BAX isoform beta BAX dependent on PubMed
    BAX upregulates PubMed
    BAX mediated by PubMed
    BAX upregulates PubMed
    BAX downregulates PubMed
    BAX enhanced by PubMed
    B-cell lymphoma/leukemia 11B isoform 2 BCL11B inhibited by PubMed
    apoptosis regulator Bcl-2 isoform alpha BCL2 downregulates PubMed
    BCL2 upregulates PubMed
    BCL2 inhibited by PubMed
    bcl-2-like protein 1 isoform Bcl-X(L) BCL2L1 interacts with PubMed
    BCL2L1 downregulates PubMed
    BCL2L1 relocalizes PubMed
    BCL2L1 downregulates PubMed
    BH3-interacting domain death agonist isoform 2 BID dependent on PubMed
    BID induces cleavage of PubMed
    BID induces cleavage of PubMed
    BID upregulates PubMed
    baculoviral IAP repeat-containing protein 2 isoform 1 BIRC2 inhibited by PubMed
    baculoviral IAP repeat-containing protein 3 BIRC3 counteracted by PubMed
    BIRC3 inhibited by PubMed
    baculoviral IAP repeat-containing protein 5 isoform 1 BIRC5 upregulates PubMed
    BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 BNIP3 downregulates PubMed
    BNIP3 upregulates PubMed
    breast cancer type 1 susceptibility protein isoform 1 BRCA1 stimulates PubMed
    BRCA1 induces phosphorylation of PubMed
    BRCA1 relocalizes PubMed
    bone marrow stromal antigen 2 precursor BST2 downregulates PubMed
    complement component 1 Q subcomponent-binding protein, mitochondrial precursor C1QBP downregulates PubMed
    C3a anaphylatoxin chemotactic receptor C3AR1 upregulates PubMed
    C5a anaphylatoxin chemotactic receptor 1 C5AR1 upregulates PubMed
    calreticulin precursor CALR upregulates PubMed
    macrophage-capping protein isoform 1 CAPG downregulates PubMed
    F-actin-capping protein subunit alpha-1 CAPZA1 upregulates PubMed
    caspase-1 isoform alpha precursor CASP1 activates PubMed
    caspase-3 isoform a preproprotein CASP3 activates PubMed
    CASP3 activates PubMed
    CASP3 cooperates with PubMed
    CASP3 regulated by PubMed
    CASP3 activates PubMed
    CASP3 induces cleavage of PubMed
    CASP3 activates PubMed
    CASP3 activates PubMed
    CASP3 activates PubMed
    CASP3 activates PubMed
    CASP3 activates PubMed
    caspase-6 isoform alpha precursor CASP6 activates PubMed
    CASP6 upregulates PubMed
    caspase-7 isoform alpha precursor CASP7 activates PubMed
    CASP7 activates PubMed
    CASP7 activates PubMed
    CASP7 upregulates PubMed
    caspase-8 isoform 1 precursor CASP8 dependent on PubMed
    CASP8 activates PubMed
    CASP8 activates PubMed
    CASP8-associated protein 2 CASP8AP2 upregulates PubMed
    caspase-9 isoform alpha precursor CASP9 activates PubMed
    CASP9 activates PubMed
    CASP9 activates PubMed
    CASP9 activates PubMed
    CASP9 activates PubMed
    CASP9 activates PubMed
    caveolin-1 isoform alpha CAV1 mediated by PubMed
    chromobox protein homolog 3 isoform a CBX3 relocalizes PubMed
    chromobox protein homolog 5 CBX5 relocalizes PubMed
    CBX5 relocalizes PubMed
    cell cycle and apoptosis regulator protein 2 isoform 1 CCAR2 downregulates PubMed
    PAT complex subunit CCDC47 precursor CCDC47 interacts with PubMed
    C-C motif chemokine 1 precursor CCL1 downregulates PubMed
    C-C motif chemokine 2 precursor CCL2 upregulates PubMed
    C-C motif chemokine 20 isoform 2 precursor CCL20 downregulates PubMed
    C-C motif chemokine 23 isoform CKbeta8-1 precursor CCL23 upregulates PubMed
    C-C motif chemokine 26 precursor CCL26 upregulates PubMed
    C-C motif chemokine 3 precursor CCL3 downregulates PubMed
    C-C motif chemokine 3-like 1 precursor CCL3L3 upregulates PubMed
    C-C motif chemokine 4 precursor CCL4 downregulates PubMed
    C-C motif chemokine 5 isoform 1 precursor CCL5 upregulates PubMed
    CCL5 upregulates PubMed
    CCL5 upregulates PubMed
    CCL5 regulates PubMed
    C-C motif chemokine 8 precursor CCL8 upregulates PubMed
    G2/mitotic-specific cyclin-B1 isoform 1 CCNB1 upregulates PubMed
    CCNB1 induces accumulation of PubMed
    CCNB1 interacts with PubMed
    CCNB1 interacts with PubMed
    CCNB1 induces release of PubMed
    CCNB1 inactivates PubMed
    CCNB1 inhibits PubMed
    CCNB1 inactivates PubMed
    CCNB1 inactivates PubMed
    CCNB1 inactivates PubMed
    CCNB1 inactivates PubMed
    G2/mitotic-specific cyclin-B2 CCNB2 inactivates PubMed
    CCNB2 inhibits PubMed
    CCNB2 inactivates PubMed
    CCNB2 inactivates PubMed
    CCNB2 inactivates PubMed
    CCNB2 inactivates PubMed
    G2/mitotic-specific cyclin-B3 isoform 3 CCNB3 inactivates PubMed
    CCNB3 inhibits PubMed
    CCNB3 inactivates PubMed
    CCNB3 inactivates PubMed
    CCNB3 inactivates PubMed
    CCNB3 inactivates PubMed
    cyclin-H isoform 1 CCNH inhibited by PubMed
    CCNH enhanced by PubMed
    cyclin-T1 isoform a CCNT1 binds PubMed
    C-C chemokine receptor type 5 CCR5 interacts with PubMed
    T-cell surface glycoprotein CD1a isoform 2 CD1A upregulates PubMed
    antigen-presenting glycoprotein CD1d isoform 2 precursor CD1D downregulates PubMed
    T-cell-specific surface glycoprotein CD28 isoform 1 precursor CD28 downregulates PubMed
    myeloid cell surface antigen CD33 isoform 1 precursor CD33 downregulates PubMed
    T-cell surface glycoprotein CD3 epsilon chain precursor CD3E antagonizes PubMed
    T-cell surface glycoprotein CD4 isoform 1 precursor CD4 downregulates PubMed
    CD4 downregulates PubMed
    CD4 downregulates PubMed
    tumor necrosis factor receptor superfamily member 5 isoform 1 precursor CD40 downregulates PubMed
    CD44 antigen isoform 1 precursor CD44 upregulates PubMed
    CD44 downregulates PubMed
    early activation antigen CD69 CD69 activates PubMed
    T-lymphocyte activation antigen CD80 precursor CD80 downregulates PubMed
    CD80 downregulates PubMed
    CD83 antigen isoform a precursor CD83 downregulates PubMed
    CD83 downregulates PubMed
    T-lymphocyte activation antigen CD86 isoform 1 precursor CD86 downregulates PubMed
    CD86 downregulates PubMed
    M-phase inducer phosphatase 1 isoform a CDC25A relocalizes PubMed
    CDC25A relocalizes PubMed
    M-phase inducer phosphatase 2 isoform 1 CDC25B relocalizes PubMed
    CDC25B relocalizes PubMed
    M-phase inducer phosphatase 3 isoform a CDC25C relocalizes PubMed
    CDC25C relocalizes PubMed
    CDC25C interacts with PubMed
    CDC25C binds PubMed
    CDC25C binds PubMed
    CDC25C complexes with PubMed
    CDC25C induces release of PubMed
    CDC25C inactivates PubMed
    CDC25C inactivates PubMed
    CDC25C inactivates PubMed
    cadherin-1 isoform 1 preproprotein CDH1 upregulates PubMed
    cyclin-dependent kinase 1 isoform 1 CDK1 inactivates PubMed
    CDK1 interacts with PubMed
    CDK1 interacts with PubMed
    CDK1 inactivates PubMed
    CDK1 inhibits PubMed
    CDK1 activates PubMed
    CDK1 inactivates PubMed
    CDK1 inactivates PubMed
    CDK1 inactivates PubMed
    cyclin-dependent kinase 7 isoform 1 CDK7 inhibited by PubMed
    CDK7 enhanced by PubMed
    cyclin-dependent kinase 9 CDK9 interacts with PubMed
    cyclin-dependent kinase inhibitor 1 isoform 1 CDKN1A activates PubMed
    CDKN1A upregulates PubMed
    CDKN1A interacts with PubMed
    CDKN1A upregulates PubMed
    CDKN1A activates PubMed
    DNA replication factor Cdt1 CDT1 cooperates with PubMed
    CCAAT/enhancer-binding protein beta isoform a CEBPB cooperates with PubMed
    CEBPB cooperates with PubMed
    CEBPB activates PubMed
    CEBPB activates PubMed
    CCAAT/enhancer-binding protein delta CEBPD involves PubMed
    CEBPD involves PubMed
    histone H3-like centromeric protein A isoform a CENPA co-localizes with PubMed
    centromere protein F CENPF upregulates PubMed
    centromere protein H CENPH co-localizes with PubMed
    centrosomal protein of 170 kDa isoform alpha CEP170 interacts with PubMed
    centrin-2 CETN2 induces accumulation of PubMed
    serine/threonine-protein kinase Chk1 isoform 1 CHEK1 activates PubMed
    CHEK1 induces phosphorylation of PubMed
    CHEK1 induces phosphorylation of PubMed
    serine/threonine-protein kinase Chk2 isoform a CHEK2 induces phosphorylation of PubMed
    CHEK2 induces phosphorylation of PubMed
    chitinase-3-like protein 1 precursor CHI3L1 upregulates PubMed
    inhibitor of nuclear factor kappa-B kinase subunit alpha isoform 1 CHUK requires PubMed
    cold-inducible RNA-binding protein isoform 1 CIRBP upregulates PubMed
    chloride intracellular channel protein 1 CLIC1 downregulates PubMed
    clathrin light chain A isoform a CLTA mediated by PubMed
    clathrin light chain B isoform a CLTB mediated by PubMed
    clathrin heavy chain 1 isoform 1 CLTC upregulates PubMed
    CLTC mediated by PubMed
    catechol O-methyltransferase isoform MB-COMT COMT interacts with PubMed
    COP9 signalosome complex subunit 2 isoform 1 COPS2 interacts with PubMed
    COP9 signalosome complex subunit 3 isoform 1 COPS3 interacts with PubMed
    COP9 signalosome complex subunit 4 isoform 1 COPS4 interacts with PubMed
    COP9 signalosome complex subunit 5 COPS5 interacts with PubMed
    COP9 signalosome complex subunit 6 COPS6 interacts with PubMed
    COPS6 interacts with PubMed
    COPS6 interacts with PubMed
    COPS6 interacts with PubMed
    COPS6 binds PubMed
    COP9 signalosome complex subunit 8 isoform 1 COPS8 interacts with PubMed
    cytochrome c oxidase subunit 4 isoform 1, mitochondrial isoform 1 precursor COX4I1 co-localizes with PubMed
    carnitine O-palmitoyltransferase 1, liver isoform isoform 1 CPT1A enhances PubMed
    carnitine O-palmitoyltransferase 1, muscle isoform isoform a CPT1B enhances PubMed
    cyclic AMP-responsive element-binding protein 1 isoform A CREB1 downregulates PubMed
    CREB-binding protein isoform a CREBBP binds PubMed
    cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM precursor CTLA4 upregulates PubMed
    lysosomal protective protein isoform a precursor CTSA upregulates PubMed
    cathepsin B isoform 1 preproprotein CTSB upregulates PubMed
    cathepsin D preproprotein CTSD upregulates PubMed
    pro-cathepsin H isoform a preproprotein CTSH upregulates PubMed
    cathepsin Z preproprotein CTSZ upregulates PubMed
    cullin-4A isoform 2 CUL4A induces PubMed
    CUL4A induces complex with PubMed
    CUL4A cooperates with PubMed
    CUL4A complexes with PubMed
    CUL4A interacts with PubMed
    CUL4A interacts with PubMed
    CUL4A interacts with PubMed
    CUL4A interacts with PubMed
    CUL4A interacts with PubMed
    CUL4A co-localizes with PubMed
    CUL4A complexes with PubMed
    CUL4A interacts with PubMed
    CUL4A binds PubMed
    cullin-4B isoform 1 CUL4B complexes with PubMed
    CUL4B interacts with PubMed
    C-X-C motif chemokine 10 precursor CXCL10 upregulates PubMed
    C-X-C motif chemokine 11 isoform 2 precursor CXCL11 upregulates PubMed
    C-X-C motif chemokine 13 precursor CXCL13 upregulates PubMed
    interleukin-8 isoform 1 precursor CXCL8 upregulates PubMed
    CXCL8 downregulates PubMed
    CXCL8 involves PubMed
    CXCL8 involves PubMed
    CXCL8 enhances PubMed
    CXCL8 upregulates PubMed
    CXCL8 upregulates PubMed
    CXCL8 upregulates PubMed
    CXCL8 enhances PubMed
    CXCL8 involves PubMed
    CXCL8 involves PubMed
    CXCL8 involves PubMed
    CXCL8 involves PubMed
    CXCL8 regulates PubMed
    cytochrome c1, heme protein, mitochondrial precursor CYC1 downregulates PubMed
    cytochrome c CYCS induces release of PubMed
    CYCS induces release of PubMed
    cytoglobin CYGB downregulates PubMed
    DDB1- and CUL4-associated factor 1 isoform 1 DCAF1 requires PubMed
    DCAF1 cooperates with PubMed
    DCAF1 binds PubMed
    DCAF1 binds PubMed
    DCAF1 requires PubMed
    DCAF1 binds PubMed
    DCAF1 recruits PubMed
    DCAF1 complexes with PubMed
    DCAF1 interacts with PubMed
    DCAF1 recruits PubMed
    DCAF1 complexes with PubMed
    DCAF1 degrades PubMed
    DCAF1 complexes with PubMed
    DCAF1 interacts with PubMed
    DCAF1 interacts with PubMed
    DCAF1 interacts with PubMed
    DCAF1 cooperates with PubMed
    DCAF1 co-localizes with PubMed
    DCAF1 binds PubMed
    DCAF1 interacts with PubMed
    DCAF1 interacts with PubMed
    DCAF1 cooperates with PubMed
    DCAF1 interacts with PubMed
    DCAF1 binds PubMed
    DCAF1 binds PubMed
    DCAF1 cooperates with PubMed
    DCAF1 cooperates with PubMed
    DCAF1 co-localizes with PubMed
    DCAF1 binds PubMed
    DCAF1 interacts with PubMed
    DCAF1 binds PubMed
    DCAF1 binds PubMed
    DDB1- and CUL4-associated factor 11 isoform 1 DCAF11 interacts with PubMed
    DDB1- and CUL4-associated factor 8 DCAF8 interacts with PubMed
    dynactin subunit 1 isoform 3 DCTN1 relocalizes PubMed
    DET1- and DDB1-associated protein 1 DDA1 interacts with PubMed
    DNA damage-binding protein 1 DDB1 enhances PubMed
    DDB1 binds PubMed
    DDB1 cooperates with PubMed
    DDB1 degrades PubMed
    DDB1 recruits PubMed
    DDB1 complexes with PubMed
    DDB1 complexes with PubMed
    DDB1 interacts with PubMed
    DDB1 induces complex with PubMed
    DDB1 interacts with PubMed
    DDB1 interacts with PubMed
    DDB1 interacts with PubMed
    DDB1 interacts with PubMed
    DDB1 co-localizes with PubMed
    DDB1 interacts with PubMed
    DDB1 binds PubMed
    DDB1 cooperates with PubMed
    DDB1 stabilized by PubMed
    DDB1 cooperates with PubMed
    DDB1 inhibits PubMed
    DDB1 interacts with PubMed
    DNA damage-binding protein 2 isoform WT DDB2 inhibits PubMed
    probable ATP-dependent RNA helicase DDX20 DDX20 interacts with PubMed
    probable ATP-dependent RNA helicase DDX5 isoform a DDX5 upregulates PubMed
    probable ATP-dependent RNA helicase DDX60 isoform 1 DDX60 upregulates PubMed
    diacylglycerol kinase kappa DGKK upregulates PubMed
    diablo IAP-binding mitochondrial protein isoform 1 precursor DIABLO induces release of PubMed
    endoribonuclease Dicer isoform 1 DICER1 downregulates PubMed
    DICER1 complexes with PubMed
    dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial isoform 1 precursor DLST upregulates PubMed
    dnaJ homolog subfamily B member 2 isoform b DNAJB2 downregulates PubMed
    dnaJ homolog subfamily B member 6 isoform a DNAJB6 facilitated by PubMed
    dynamin-1-like protein isoform 3 DNM1L downregulates PubMed
    DNM1L relocalizes PubMed
    protein C-mannosyl-transferase DPY19L1 isoform 2 DPY19L1 interacts with PubMed
    protein C-mannosyl-transferase DPY19L3 DPY19L3 interacts with PubMed
    dual oxidase 2 isoform 1 precursor DUOX2 downregulates PubMed
    dual specificity protein phosphatase 1 DUSP1 downregulates PubMed
    cytoplasmic dynein 1 heavy chain 1 DYNC1H1 relocalizes PubMed
    DYNC1H1 interacts with PubMed
    DYNC1H1 interacts with PubMed
    cytoplasmic dynein 1 intermediate chain 2 isoform 1 DYNC1I2 interacts with PubMed
    cytoplasmic dynein 1 light intermediate chain 1 isoform 1 DYNC1LI1 interacts with PubMed
    dynein light chain Tctex-type 1 isoform 1 DYNLT1 interacts with PubMed
    dysferlin isoform 8 DYSF upregulates PubMed
    interleukin-27 subunit beta precursor EBI3 downregulates PubMed
    enoyl-CoA delta isomerase 1, mitochondrial isoform 1 precursor ECI1 downregulates PubMed
    early endosome antigen 1 EEA1 upregulates PubMed
    elongation factor 2 EEF2 inhibited by PubMed
    eukaryotic translation initiation factor 4E isoform 1 EIF4E downregulates PubMed
    eukaryotic translation initiation factor 4E-binding protein 1 EIF4EBP1 downregulates PubMed
    crossover junction endonuclease EME1 isoform 2 EME1 interacts with PubMed
    EME1 induces phosphorylation of PubMed
    EME1 complexes with PubMed
    histone acetyltransferase p300 isoform 1 EP300 interacts with PubMed
    EP300 recruits PubMed
    EP300 activates PubMed
    EP300 activates PubMed
    EP300 enhanced by PubMed
    EP300 binds PubMed
    EP300 binds PubMed
    DNA excision repair protein ERCC-1 isoform 2 ERCC1 complexes with PubMed
    DNA repair endonuclease XPF ERCC4 complexes with PubMed
    electron transfer flavoprotein subunit alpha, mitochondrial isoform a ETFA downregulates PubMed
    electron transfer flavoprotein subunit beta isoform 1 ETFB downregulates PubMed
    persulfide dioxygenase ETHE1, mitochondrial isoform 1 ETHE1 downregulates PubMed
    RNA-binding protein EWS isoform 1 EWSR1 upregulates PubMed
    ezrin EZR downregulates PubMed
    EZR upregulates PubMed
    proteinase-activated receptor 1 isoform 2 F2R blocks PubMed
    Fanconi anemia group D2 protein isoform a FANCD2 increases PubMed
    tumor necrosis factor receptor superfamily member 6 isoform 1 precursor FAS cooperates with PubMed
    high affinity immunoglobulin epsilon receptor subunit gamma precursor FCER1G upregulates PubMed
    low affinity immunoglobulin gamma Fc region receptor II-c precursor FCGR2C upregulates PubMed
    low affinity immunoglobulin gamma Fc region receptor III-A isoform a FCGR3A antagonizes PubMed
    fumarate hydratase, mitochondrial FH upregulates PubMed
    filamin-A isoform 2 FLNA upregulates PubMed
    filamin-B isoform 1 FLNB upregulates PubMed
    protein c-Fos FOS regulated by PubMed
    FOS activates PubMed
    forkhead box protein M1 isoform 2 FOXM1 downregulates PubMed
    forkhead box protein O3 isoform 1 FOXO3 inhibits PubMed
    FOXO3 inhibits PubMed
    ferritin heavy chain FTH1 upregulates PubMed
    ferritin light chain FTL downregulates PubMed
    ras GTPase-activating protein-binding protein 2 isoform a G3BP2 upregulates PubMed
    glucose-6-phosphate 1-dehydrogenase isoform a G6PD upregulates PubMed
    growth arrest and DNA damage-inducible protein GADD45 alpha isoform 1 GADD45A upregulates PubMed
    glyceraldehyde-3-phosphate dehydrogenase isoform 1 GAPDH downregulates PubMed
    GAPDH downregulates PubMed
    guanylate-binding protein 5 isoform 1 GBP5 antagonizes PubMed
    gem-associated protein 2 isoform alpha GEMIN2 interacts with PubMed
    gem-associated protein 4 GEMIN4 interacts with PubMed
    gem-associated protein 6 GEMIN6 interacts with PubMed
    gem-associated protein 7 GEMIN7 interacts with PubMed
    glial fibrillary acidic protein isoform 1 GFAP interacts with PubMed
    ADP-ribosylation factor-binding protein GGA1 isoform 1 GGA1 co-localizes with PubMed
    ADP-ribosylation factor-binding protein GGA2 GGA2 co-localizes with PubMed
    ADP-ribosylation factor-binding protein GGA3 isoform short GGA3 co-localizes with PubMed
    glutamate dehydrogenase 2, mitochondrial precursor GLUD2 downregulates PubMed
    guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 isoform 1 GNB1 upregulates PubMed
    N-acetylglucosamine-6-sulfatase precursor GNS upregulates PubMed
    Golgi phosphoprotein 3 GOLPH3 interacts with PubMed
    glucose-6-phosphate isomerase isoform 2 GPI downregulates PubMed
    COP9 signalosome complex subunit 1 isoform 2 GPS1 interacts with PubMed
    epididymal secretory glutathione peroxidase isoform 1 precursor GPX5 upregulates PubMed
    glycogen synthase kinase-3 beta isoform 1 GSK3B downregulates PubMed
    gelsolin isoform a precursor GSN upregulates PubMed
    GSN inhibited by PubMed
    glutathione S-transferase kappa 1 isoform a GSTK1 downregulates PubMed
    glutathione S-transferase P GSTP1 upregulates PubMed
    transcription initiation factor IIB GTF2B binds PubMed
    general transcription factor IIH subunit 1 GTF2H1 inhibited by PubMed
    GTF2H1 enhanced by PubMed
    histone H2AX H2AX interacts with PubMed
    H2AX induces phosphorylation of PubMed
    H2AX induces phosphorylation of PubMed
    H2AX activates PubMed
    hydroxyacyl-coenzyme A dehydrogenase, mitochondrial isoform 2 precursor HADH enhances PubMed
    trifunctional enzyme subunit alpha, mitochondrial precursor HADHA downregulates PubMed
    histone acetyltransferase type B catalytic subunit HAT1 complexes with PubMed
    HAT1 interacts with PubMed
    histone deacetylase 1 HDAC1 depletes PubMed
    HDAC1 binds PubMed
    HDAC1 depletes PubMed
    HDAC1 cooperates with PubMed
    histone deacetylase 2 HDAC2 depletes PubMed
    HDAC2 cooperates with PubMed
    histone deacetylase 3 isoform 2 HDAC3 depletes PubMed
    HDAC3 binds PubMed
    HDAC3 depletes PubMed
    histone deacetylase 8 isoform 2 HDAC8 depletes PubMed
    hepatoma-derived growth factor isoform a HDGF downregulates PubMed
    hepatoma-derived growth factor-related protein 2 isoform 2 HDGFL2 interacts with PubMed
    E3 ISG15--protein ligase HERC5 HERC5 upregulates PubMed
    hypoxia-inducible factor 1-alpha isoform 1 HIF1A regulates PubMed
    HIF1A upregulates PubMed
    hexokinase-1 isoform HKI HK1 induces accumulation of PubMed
    HK1 upregulates PubMed
    HK1 upregulates PubMed
    hexokinase-2 isoform 1 HK2 upregulates PubMed
    HLA class I histocompatibility antigen, A alpha chain isoform A*03:01:01:01 precursor HLA-A upregulates PubMed
    major histocompatibility complex, class I, B precursor HLA-B interacts with PubMed
    HLA class I histocompatibility antigen, C alpha chain precursor HLA-C interacts with PubMed
    helicase-like transcription factor isoform 2 HLTF downregulates PubMed
    HLTF binds PubMed
    HLTF recruits PubMed
    HLTF downregulates PubMed
    HLTF downregulates PubMed
    heterogeneous nuclear ribonucleoproteins A2/B1 isoform A2 HNRNPA2B1 regulated by PubMed
    heterogeneous nuclear ribonucleoprotein D0 isoform c HNRNPD downregulates PubMed
    heterogeneous nuclear ribonucleoprotein F HNRNPF regulated by PubMed
    heterogeneous nuclear ribonucleoprotein H isoform a HNRNPH1 regulated by PubMed
    heterogeneous nuclear ribonucleoprotein U isoform b HNRNPU modulated by PubMed
    hypoxanthine-guanine phosphoribosyltransferase HPRT1 downregulates PubMed
    3-hydroxyacyl-CoA dehydrogenase type-2 isoform 1 HSD17B10 downregulates PubMed
    peroxisomal multifunctional enzyme type 2 isoform 2 HSD17B4 upregulates PubMed
    heat shock factor protein 1 HSF1 inhibits PubMed
    HSF1 upregulates PubMed
    heat shock protein HSP 90-beta isoform a HSP90AB1 upregulates PubMed
    heat shock 70 kDa protein 1A HSPA1A interacts with PubMed
    HSPA1A binds PubMed
    HSPA1A inhibited by PubMed
    HSPA1A inhibited by PubMed
    HSPA1A competes with PubMed
    heat shock 70 kDa protein 1B HSPA1B interacts with PubMed
    HSPA1B competes with PubMed
    heat shock-related 70 kDa protein 2 HSPA2 upregulates PubMed
    HSPA2 interacts with PubMed
    HSPA2 competes with PubMed
    heat shock 70 kDa protein 4 HSPA4 interacts with PubMed
    HSPA4 competes with PubMed
    endoplasmic reticulum chaperone BiP precursor HSPA5 upregulates PubMed
    HSPA5 interacts with PubMed
    HSPA5 upregulates PubMed
    HSPA5 competes with PubMed
    heat shock 70 kDa protein 6 HSPA6 interacts with PubMed
    HSPA6 competes with PubMed
    heat shock cognate 71 kDa protein isoform 1 HSPA8 interacts with PubMed
    HSPA8 competes with PubMed
    stress-70 protein, mitochondrial precursor HSPA9 interacts with PubMed
    HSPA9 competes with PubMed
    heat shock protein beta-1 HSPB1 competes with PubMed
    HSPB1 inhibited by PubMed
    60 kDa heat shock protein, mitochondrial HSPD1 downregulates PubMed
    hypoxia up-regulated protein 1 isoform 1 precursor HYOU1 upregulates PubMed
    isocitrate dehydrogenase IDH2 downregulates PubMed
    indoleamine 2,3-dioxygenase 1 IDO1 downregulates PubMed
    gamma-interferon-inducible protein 16 isoform 1 IFI16 antagonizes PubMed
    interferon alpha-inducible protein 27, mitochondrial isoform 2 IFI27 upregulates PubMed
    IFI27 upregulates PubMed
    interferon-induced 35 kDa protein isoform 1 IFI35 upregulates PubMed
    interferon-induced protein 44-like isoform 1 IFI44L upregulates PubMed
    IFI44L upregulates PubMed
    interferon alpha-inducible protein 6 isoform c precursor IFI6 upregulates PubMed
    interferon-induced helicase C domain-containing protein 1 IFIH1 upregulates PubMed
    interferon-induced protein with tetratricopeptide repeats 1 isoform 1 IFIT1 antagonizes PubMed
    IFIT1 upregulates PubMed
    IFIT1 upregulates PubMed
    interferon-induced protein with tetratricopeptide repeats 2 IFIT2 upregulates PubMed
    IFIT2 upregulates PubMed
    interferon-induced protein with tetratricopeptide repeats 3 isoform a IFIT3 upregulates PubMed
    interferon-induced transmembrane protein 1 IFITM1 interacts with PubMed
    IFITM1 upregulates PubMed
    IFITM1 interacts with PubMed
    interferon-induced transmembrane protein 2 IFITM2 upregulates PubMed
    IFITM2 interacts with PubMed
    interferon-induced transmembrane protein 3 IFITM3 upregulates PubMed
    IFITM3 interacts with PubMed
    interferon alpha-1/13 precursor IFNA1 abrogated by PubMed
    IFNA1 inhibits PubMed
    IFNA1 inhibits PubMed
    IFNA1 upregulates PubMed
    interferon alpha-10 precursor IFNA10 inhibits PubMed
    IFNA13 inhibits PubMed
    interferon alpha-14 precursor IFNA14 inhibits PubMed
    interferon alpha-16 precursor IFNA16 inhibits PubMed
    interferon alpha-17 precursor IFNA17 inhibits PubMed
    interferon alpha-2 precursor IFNA2 antagonizes PubMed
    IFNA2 inhibits PubMed
    interferon alpha-21 precursor IFNA21 inhibits PubMed
    interferon alpha-4 precursor IFNA4 inhibits PubMed
    interferon alpha-5 precursor IFNA5 inhibits PubMed
    interferon alpha-6 precursor IFNA6 inhibits PubMed
    interferon alpha-7 precursor IFNA7 inhibits PubMed
    interferon alpha-8 precursor IFNA8 inhibits PubMed
    interferon beta precursor IFNB1 inhibits PubMed
    interferon gamma precursor IFNG inhibits PubMed
    IFNG downregulates PubMed
    IFNG downregulates PubMed
    IFNG upregulates PubMed
    inhibitor of nuclear factor kappa-B kinase subunit beta isoform 1 IKBKB requires PubMed
    IKBKB induces phosphorylation of PubMed
    interleukin-10 isoform 1 precursor IL10 upregulates PubMed
    IL10 modulates PubMed
    interleukin-12 subunit alpha isoform 1 precursor IL12A modulates PubMed
    IL12A downregulates PubMed
    IL12A downregulates PubMed
    IL12A downregulates PubMed
    interleukin-12 subunit beta precursor IL12B downregulates PubMed
    interleukin-1 alpha precursor IL1A upregulates PubMed
    interleukin-1 beta proprotein IL1B activates PubMed
    interleukin-2 precursor IL2 downregulates PubMed
    IL2 downregulates PubMed
    interleukin-4 isoform 1 precursor IL4 downregulates PubMed
    interleukin-6 isoform 1 precursor IL6 upregulates PubMed
    IL6 upregulates PubMed
    IL6 involves PubMed
    IL6 involves PubMed
    IL6 enhances PubMed
    IL6 upregulates PubMed
    IL6 upregulates PubMed
    IL6 upregulates PubMed
    IL6 enhances PubMed
    IL6 involves PubMed
    IL6 involves PubMed
    IL6 involves PubMed
    IL6 involves PubMed
    IL6 downregulates PubMed
    IL6 upregulates PubMed
    IL6 upregulates PubMed
    IL6 upregulates PubMed
    interleukin enhancer-binding factor 3 isoform b ILF3 downregulates PubMed
    inner centromere protein isoform 2 INCENP upregulates PubMed
    INCENP relocalizes PubMed
    INCENP downregulates PubMed
    insulin preproprotein INS inhibits PubMed
    INS inhibits PubMed
    INS inhibits PubMed
    importin-5 IPO5 interacts with PubMed
    IPO5 regulates PubMed
    importin-7 IPO7 imported by PubMed
    interferon regulatory factor 3 isoform 1 IRF3 induces cleavage of PubMed
    IRF3 inhibits PubMed
    IRF3 degrades PubMed
    interferon regulatory factor 7 isoform a IRF7 upregulates PubMed
    ubiquitin-like protein ISG15 ISG15 upregulates PubMed
    ISG15 upregulates PubMed
    interferon-stimulated gene 20 kDa protein isoform a ISG20 upregulates PubMed
    isochorismatase domain-containing protein 2 isoform 2 ISOC2 downregulates PubMed
    integrin alpha-5 precursor ITGA5 upregulates PubMed
    integrin alpha-6 isoform b preproprotein ITGA6 upregulates PubMed
    integrin alpha-M isoform 2 precursor ITGAM upregulates PubMed
    integrin alpha-X isoform 2 precursor ITGAX upregulates PubMed
    integrin beta-1 isoform 1A precursor ITGB1 upregulates PubMed
    integrin beta-2 isoform 1 precursor ITGB2 upregulates PubMed
    transcription factor Jun JUN involves PubMed
    JUN involves PubMed
    JUN regulated by PubMed
    JUN activates PubMed
    lysine--tRNA ligase isoform 2 KARS1 relocalizes PubMed
    KARS1 inhibits PubMed
    far upstream element-binding protein 2 isoform 1 KHSRP upregulates PubMed
    kinesin-like protein KIF22 isoform 1 KIF22 upregulates PubMed
    kinesin-like protein KIF2C isoform 1 KIF2C upregulates PubMed
    kinesin-like protein KIFC1 KIFC1 upregulates PubMed
    importin subunit alpha-5 KPNA1 binds PubMed
    KPNA1 interacts with PubMed
    KPNA1 binds PubMed
    KPNA1 interacts with PubMed
    KPNA1 imported by PubMed
    KPNA1 interacts with PubMed
    importin subunit alpha-1 KPNA2 binds PubMed
    KPNA2 binds PubMed
    KPNA2 binds PubMed
    KPNA2 imported by PubMed
    KPNA2 interacts with PubMed
    KPNA2 interacts with PubMed
    importin subunit alpha-3 KPNA4 binds PubMed
    importin subunit beta-1 isoform 1 KPNB1 interacts with PubMed
    KPNB1 regulates PubMed
    lysosome-associated membrane glycoprotein 1 precursor LAMP1 inhibits PubMed
    LAMP1 abrogates PubMed
    LAMP1 downregulates PubMed
    lysosome-associated membrane glycoprotein 2 isoform C precursor LAMP2 reduces PubMed
    linker for activation of T-cells family member 2 LAT2 upregulates PubMed
    mitochondrial proton/calcium exchanger protein precursor LETM1 downregulates PubMed
    galectin-3 isoform 2 LGALS3 upregulates PubMed
    lamin isoform A LMNA downregulates PubMed
    LMNA co-localizes with PubMed
    lamin-B1 isoform 1 LMNB1 downregulates PubMed
    LMNB1 co-localizes with PubMed
    lamin-B2 LMNB2 downregulates PubMed
    LMNB2 co-localizes with PubMed
    LIM domain only protein 7 isoform 3 LMO7 upregulates PubMed
    dual specificity mitogen-activated protein kinase kinase 1 isoform 1 MAP2K1 cooperates with PubMed
    dual specificity mitogen-activated protein kinase kinase 2 MAP2K2 cooperates with PubMed
    MAP2K2 decreases phosphorylation of PubMed
    MAP2K2 downregulates PubMed
    dual specificity mitogen-activated protein kinase kinase 7 isoform 3 MAP2K7 induces phosphorylation of PubMed
    MAP2K7 activates PubMed
    mitogen-activated protein kinase kinase kinase 7 isoform A MAP3K7 enhances PubMed
    MAP3K7 activates PubMed
    MAP3K7 interacts with PubMed
    MAP3K7 induces phosphorylation of PubMed
    MAP3K7 induces phosphorylation of PubMed
    mitogen-activated protein kinase 1 MAPK1 activates PubMed
    mitogen-activated protein kinase 11 MAPK11 involves PubMed
    MAPK11 involves PubMed
    mitogen-activated protein kinase 13 MAPK13 involves PubMed
    MAPK13 regulated by PubMed
    mitogen-activated protein kinase 14 isoform 1 MAPK14 cooperates with PubMed
    MAPK14 cooperates with PubMed
    mitogen-activated protein kinase 3 isoform 1 MAPK3 activates PubMed
    mitogen-activated protein kinase 8 isoform alpha2 MAPK8 involves PubMed
    MAPK8 involves PubMed
    MAPK8 involves PubMed
    MAPK8 activates PubMed
    MAP kinase-activated protein kinase 2 isoform 1 MAPKAPK2 requires PubMed
    microtubule-associated protein RP/EB family member 1 MAPRE1 relocalizes PubMed
    MAPRE1 interacts with PubMed
    macrophage receptor MARCO MARCO stimulates PubMed
    matrin-3 isoform a MATR3 upregulates PubMed
    MATR3 interacts with PubMed
    induced myeloid leukemia cell differentiation protein Mcl-1 isoform 1 MCL1 interacts with PubMed
    protein MCM10 homolog isoform 2 MCM10 depletes PubMed
    MCM10 enhances PubMed
    MCM10 degrades PubMed
    DNA replication licensing factor MCM3 isoform 1 MCM3 downregulates PubMed
    DNA replication licensing factor MCM5 MCM5 downregulates PubMed
    DNA replication licensing factor MCM6 MCM6 downregulates PubMed
    malate dehydrogenase, mitochondrial isoform 1 precursor MDH2 downregulates PubMed
    mitofusin-2 MFN2 downregulates PubMed
    glutathione S-transferase 3, mitochondrial MGST3 downregulates PubMed
    macrophage migration inhibitory factor MIF upregulates PubMed
    protein MIS12 homolog MIS12 relocalizes PubMed
    mitotic interactor and substrate of PLK1 MISP upregulates PubMed
    MAP kinase-interacting serine/threonine-protein kinase 2 isoform 1 MKNK2 downregulates PubMed
    interstitial collagenase isoform 1 preproprotein MMP1 downregulates PubMed
    CDK-activating kinase assembly factor MAT1 isoform 1 MNAT1 inhibited by PubMed
    MNAT1 enhanced by PubMed
    mannosyl-oligosaccharide glucosidase isoform 1 MOGS interacts with PubMed
    moesin MSN downregulates PubMed
    metallothionein-3 MT3 downregulates PubMed
    metastasis-associated protein MTA2 isoform 1 MTA2 interacts with PubMed
    mitochondrial carrier homolog 2 isoform 1 MTCH2 interacts with PubMed
    protein LYRIC isoform 1 MTDH upregulates PubMed
    crossover junction endonuclease MUS81 isoform 2 MUS81 downregulates PubMed
    MUS81 affects PubMed
    MUS81 interacts with PubMed
    MUS81 degrades PubMed
    MUS81 induces ubiquitination of PubMed
    MUS81 interacts with PubMed
    MUS81 complexes with PubMed
    interferon-induced GTP-binding protein Mx1 isoform a MX1 upregulates PubMed
    MX1 upregulates PubMed
    MX1 downregulates PubMed
    interferon-induced GTP-binding protein Mx2 MX2 upregulates PubMed
    MX2 upregulates PubMed
    myeloid differentiation primary response protein MyD88 isoform 2 MYD88 cooperates with PubMed
    myosin-11 isoform SM1A MYH11 upregulates PubMed
    myosin-9 MYH9 upregulates PubMed
    myosin light polypeptide 6 isoform 1 MYL6 upregulates PubMed
    unconventional myosin-Ig MYO1G downregulates PubMed
    nuclear receptor coactivator 1 isoform 1 NCOA1 enhances PubMed
    NADH dehydrogenase NDUFS8 interacts with PubMed
    NDUFV3 upregulates PubMed
    E3 ubiquitin-protein ligase NEDD4-like isoform 3 NEDD4L interacts with PubMed
    neurofilament medium polypeptide isoform 1 NEFM downregulates PubMed
    nuclear factor of activated T-cells, cytoplasmic 1 isoform B NFATC1 induces PubMed
    NFATC1 stimulates PubMed
    NFATC1 upregulates PubMed
    nuclear factor of activated T-cells, cytoplasmic 2 isoform B NFATC2 upregulates PubMed
    nuclear factor of activated T-cells, cytoplasmic 3 isoform 2 NFATC3 upregulates PubMed
    nuclear factor of activated T-cells, cytoplasmic 4 isoform 2 NFATC4 upregulates PubMed
    nuclear factor NF-kappa-B p105 subunit isoform 1 NFKB1 activates PubMed
    NFKB1 activates PubMed
    NFKB1 activates PubMed
    NFKB1 enhances PubMed
    NFKB1 involves PubMed
    NFKB1 involves PubMed
    NFKB1 involves PubMed
    NFKB1 involves PubMed
    NFKB1 inhibits PubMed
    NFKB1 regulates PubMed
    NFKB1 activates PubMed
    NFKB1 regulated by PubMed
    NFKB1 activates PubMed
    NFKB1 inhibits PubMed
    NFKB1 activates PubMed
    NFKB1 inhibits PubMed
    NFKB1 activates PubMed
    NFKB1 activates PubMed
    NFKB1 activates PubMed
    NFKB1 activates PubMed
    NFKB1 interacts with PubMed
    NFKB1 downregulates PubMed
    NFKB1 inhibits PubMed
    nuclear factor NF-kappa-B p100 subunit isoform b NFKB2 induces phosphorylation of PubMed
    NF-kappa-B inhibitor alpha NFKBIA induces phosphorylation of PubMed
    NFKBIA upregulates PubMed
    NFKBIA upregulates PubMed
    NF-kappa-B inhibitor beta isoform 1 NFKBIB induces phosphorylation of PubMed
    NFKBIB upregulates PubMed
    beta-nerve growth factor precursor NGF inhibited by PubMed
    nucleotide-binding oligomerization domain-containing protein 2 isoform 2 NOD2 upregulates PubMed
    non-POU domain-containing octamer-binding protein isoform 1 NONO upregulates PubMed
    nitric oxide synthase, inducible NOS2 upregulates PubMed
    nucleophosmin isoform 1 NPM1 downregulates PubMed
    glucocorticoid receptor isoform alpha NR3C1 interacts with PubMed
    NR3C1 interacts with PubMed
    NR3C1 activates PubMed
    NR3C1 activates PubMed
    NR3C1 activates PubMed
    NR3C1 complexes with PubMed
    NR3C1 activates PubMed
    NR3C1 activates PubMed
    NR3C1 activates PubMed
    NR3C1 activates PubMed
    NR3C1 activates PubMed
    NR3C1 activates PubMed
    NR3C1 activates PubMed
    nuclear receptor subfamily 4immunitygroup A member 1 isoform 1 NR4A1 downregulates PubMed
    high affinity nerve growth factor receptor isoform 2 precursor NTRK1 downregulates PubMed
    nuclear pore complex protein Nup153 isoform 2 NUP153 interacts with PubMed
    nucleoporin NUP42 isoform 2 NUP42 affects PubMed
    NUP42 binds PubMed
    NUP42 interacts with PubMed
    nucleoporin p54 isoform 1 NUP54 binds PubMed
    nuclear pore complex protein Nup85 isoform 1 NUP85 induces accumulation of PubMed
    2'-5'-oligoadenylate synthase 1 isoform 3 OAS1 antagonizes PubMed
    2'-5'-oligoadenylate synthase 2 isoform 3 OAS2 upregulates PubMed
    2'-5'-oligoadenylate synthase 3 isoform 1 OAS3 upregulates PubMed
    2'-5'-oligoadenylate synthase-like protein isoform c OASL upregulates PubMed
    2-oxoglutarate dehydrogenase complex component E1 isoform 1 precursor OGDH upregulates PubMed
    dynamin-like 120 kDa protein, mitochondrial isoform 1 preproprotein OPA1 upregulates PubMed
    protein disulfide-isomerase precursor P4HB upregulates PubMed
    proliferation-associated protein 2G4 PA2G4 downregulates PubMed
    poly(A) polymerase alpha isoform 1 PAPOLA decreases phosphorylation of PubMed
    poly PARP1 recruits PubMed
    PARP1 induces cleavage of PubMed
    pericentrin isoform 1 PCNT induces accumulation of PubMed
    proprotein convertase subtilisin/kexin type 5 isoform PC6A preproprotein PCSK5 cleaved by PubMed
    proprotein convertase subtilisin/kexin type 6 isoform PACE4-AI preproprotein PCSK6 involves PubMed
    PCSK6 cleaves PubMed
    PCSK6 cleaved by PubMed
    pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial isoform 1 precursor PDHA1 induces phosphorylation of PubMed
    protein disulfide-isomerase A3 precursor PDIA3 downregulates PubMed
    pyruvate dehydrogenase kinase, isozyme 4 PDK4 enhances PubMed
    PDK4 enhances PubMed
    platelet endothelial cell adhesion molecule precursor PECAM1 upregulates PubMed
    profilin-1 isoform 2 PFN1 downregulates PubMed
    membrane-associated progesterone receptor component 2 PGRMC2 upregulates PubMed
    prohibitin 1 isoform 1 PHB1 downregulates PubMed
    PHB1 modulates PubMed
    phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform PIK3CA involves PubMed
    PIK3CA involves PubMed
    phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform 2 PIK3CB involves PubMed
    PIK3CB involves PubMed
    phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform 1 PIK3CD involves PubMed
    PIK3CD involves PubMed
    phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform PIK3CG involves PubMed
    PIK3CG involves PubMed
    pyruvate kinase PKM isoform a PKM upregulates PubMed
    plectin isoform 1c PLEC upregulates PubMed
    serine/threonine-protein kinase PLK1 PLK1 affects PubMed
    PLK1 interacts with PubMed
    DNA polymerase alpha catalytic subunit isoform 1 POLA1 downregulates PubMed
    DNA-directed RNA polymerase II subunit RPB1 POLR2A activates PubMed
    DNA-directed RNA polymerase II subunit RPB3 POLR2C activates PubMed
    DNA-directed RNA polymerase II subunit RPB4 POLR2D activates PubMed
    DNA-directed RNA polymerases I, II, and III subunit RPABC1 isoform a POLR2E activates PubMed
    DNA-directed RNA polymerases I, II, and III subunit RPABC2 isoform 1 POLR2F activates PubMed
    DNA-directed RNA polymerase II subunit RPB7 POLR2G activates PubMed
    DNA-directed RNA polymerases I, II, and III subunit RPABC3 isoform 2 POLR2H activates PubMed
    DNA-directed RNA polymerase II subunit RPB9 POLR2I activates PubMed
    DNA-directed RNA polymerase II subunit RPB11-a isoform 1 POLR2J activates PubMed
    DNA-directed RNA polymerases I, II, and III subunit RPABC4 POLR2K activates PubMed
    DNA-directed RNA polymerases I, II, and III subunit RPABC5 POLR2L activates PubMed
    protein GRINL1A isoform 1 POLR2M activates PubMed
    ribonuclease P protein subunit p29 POP4 downregulates PubMed
    peroxisome proliferator-activated receptor delta isoform 1 PPARD cooperates with PubMed
    PPARD enhances PubMed
    PPARD enhances PubMed
    PPARD interacts with PubMed
    peptidyl-prolyl cis-trans isomerase A isoform 1 PPIA interacts with PubMed
    PPIA enhanced by PubMed
    PPIA isomerized by PubMed
    serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform isoform 1 PPP2CA binds PubMed
    PPP2CA upregulates PubMed
    PPP2CA activates PubMed
    serine/threonine-protein phosphatase 2A catalytic subunit beta isoform PPP2CB binds PubMed
    PPP2CB upregulates PubMed
    PPP2CB activates PubMed
    serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform isoform 1 PPP2R1A interacts with PubMed
    PPP2R1A interacts with PubMed
    PPP2R1A interacts with PubMed
    PPP2R1A binds PubMed
    PPP2R1A upregulates PubMed
    PPP2R1A activates PubMed
    serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform a PPP2R1B binds PubMed
    PPP2R1B upregulates PubMed
    PPP2R1B activates PubMed
    serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform isoform 1 PPP2R2A binds PubMed
    PPP2R2A activates PubMed
    PPP2R2A upregulates PubMed
    PPP2R2A activates PubMed
    serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform isoform a PPP2R2B binds PubMed
    PPP2R2B activates PubMed
    PPP2R2B upregulates PubMed
    PPP2R2B activates PubMed
    protein phosphatase 2, regulatory subunit B, gamma isoform b PPP2R2C activates PubMed
    PPP2R2C upregulates PubMed
    PPP2R2C activates PubMed
    serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha isoform 1 PPP2R3A binds PubMed
    PPP2R3A activates PubMed
    PPP2R3A upregulates PubMed
    PPP2R3A activates PubMed
    serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform isoform 1 PPP2R5A binds PubMed
    PPP2R5A upregulates PubMed
    PPP2R5A activates PubMed
    serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform PPP2R5B binds PubMed
    PPP2R5B upregulates PubMed
    PPP2R5B activates PubMed
    serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform a PPP2R5C binds PubMed
    PPP2R5C upregulates PubMed
    PPP2R5C activates PubMed
    serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform isoform 1 PPP2R5D binds PubMed
    PPP2R5D upregulates PubMed
    PPP2R5D activates PubMed
    serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform isoform a PPP2R5E binds PubMed
    PPP2R5E upregulates PubMed
    PPP2R5E activates PubMed
    5'-AMP-activated protein kinase catalytic subunit alpha-1 isoform 1 PRKAA1 phosphorylated by PubMed
    5'-AMP-activated protein kinase catalytic subunit alpha-2 PRKAA2 phosphorylated by PubMed
    5'-AMP-activated protein kinase subunit beta-1 PRKAB1 phosphorylated by PubMed
    5'-AMP-activated protein kinase subunit beta-2 PRKAB2 phosphorylated by PubMed
    cAMP-dependent protein kinase catalytic subunit alpha isoform Calpha1 PRKACA interacts with PubMed
    PRKACA phosphorylated by PubMed
    cAMP-dependent protein kinase catalytic subunit beta isoform 2 PRKACB phosphorylated by PubMed
    cAMP-dependent protein kinase catalytic subunit gamma PRKACG phosphorylated by PubMed
    5'-AMP-activated protein kinase subunit gamma-1 isoform 1 PRKAG1 phosphorylated by PubMed
    5'-AMP-activated protein kinase subunit gamma-2 isoform a PRKAG2 phosphorylated by PubMed
    cAMP-dependent protein kinase type I-alpha regulatory subunit isoform a PRKAR1A phosphorylated by PubMed
    cAMP-dependent protein kinase type I-beta regulatory subunit PRKAR1B phosphorylated by PubMed
    cAMP-dependent protein kinase type II-alpha regulatory subunit isoform a PRKAR2A phosphorylated by PubMed
    cAMP-dependent protein kinase type II-beta regulatory subunit PRKAR2B phosphorylated by PubMed
    protein kinase C iota type PRKCI regulated by PubMed
    protein kinase C zeta type isoform 1 PRKCZ regulated by PubMed
    26S proteasome non-ATPase regulatory subunit 2 isoform 1 PSMD2 interacts with PubMed
    26S proteasome non-ATPase regulatory subunit 4 isoform 2 PSMD4 interacts with PubMed
    prostaglandin G/H synthase 2 precursor PTGS2 downregulates PubMed
    serine/threonine-protein phosphatase 2A activator isoform b PTPA binds PubMed
    PTPA activates PubMed
    PTPA upregulates PubMed
    PTPA activates PubMed
    poliovirus receptor isoform alpha precursor PVR upregulates PubMed
    PVR upregulates PubMed
    peroxidasin-like protein precursor PXDNL upregulates PubMed
    ras-related protein Rab-7a RAB7A upregulates PubMed
    cell cycle checkpoint protein RAD17 isoform 1 RAD17 requires PubMed
    double-strand-break repair protein rad21 homolog RAD21 downregulates PubMed
    UV excision repair protein RAD23 homolog A isoform 1 RAD23A binds PubMed
    RAD23A binds PubMed
    RAD23A complexes with PubMed
    RAD23A binds PubMed
    RAD23A cooperates with PubMed
    RAD23A inhibits PubMed
    RAD23A binds PubMed
    RAD23A inhibited by PubMed
    DNA repair protein RAD51 homolog 1 isoform 1 RAD51 inhibits PubMed
    RAD51 stimulates PubMed
    ras-related protein Ral-A precursor RALA upregulates PubMed
    histone-binding protein RBBP7 isoform 2 RBBP7 complexes with PubMed
    RBBP7 interacts with PubMed
    retinol dehydrogenase 11 isoform 1 RDH11 upregulates PubMed
    radixin isoform 2 RDX downregulates PubMed
    proto-oncogene c-Rel isoform 1 REL upregulates PubMed
    transcription factor p65 isoform 1 RELA activates PubMed
    RELA regulated by PubMed
    RELA induces phosphorylation of PubMed
    RELA inhibits PubMed
    RELA downregulates PubMed
    RELA cooperates with PubMed
    RELA inhibits PubMed
    RELA activates PubMed
    transcription factor RelB isoform 1 RELB interacts with PubMed
    RELB cooperates with PubMed
    RELB interacts with PubMed
    transforming protein RhoA isoform 1 precursor RHOA upregulates PubMed
    rho-related GTP-binding protein RhoB RHOB upregulates PubMed
    rho-related GTP-binding protein RhoG RHOG upregulates PubMed
    antiviral innate immune response receptor RIG-I isoform 1 RIGI upregulates PubMed
    RIGI upregulates PubMed
    receptor-interacting serine/threonine-protein kinase 1 isoform 1 RIPK1 upregulates PubMed
    GTP-binding protein Rit1 isoform 2 RIT1 induces complex with PubMed
    proto-oncogene tyrosine-protein kinase ROS isoform 1 precursor ROS1 upregulates PubMed
    replication protein A 70 kDa DNA-binding subunit isoform 1 RPA1 interacts with PubMed
    replication protein A 32 kDa subunit isoform 1 RPA2 complexes with PubMed
    RPA2 co-localizes with PubMed
    RPA2 induces phosphorylation of PubMed
    large ribosomal subunit protein uL5 isoform 1 RPL11 downregulates PubMed
    large ribosomal subunit protein eL13 isoform 1 RPL13 downregulates PubMed
    large ribosomal subunit protein uL23 RPL23A downregulates PubMed
    large ribosomal subunit protein eL29 RPL29 downregulates PubMed
    large ribosomal subunit protein uL10 RPLP0 downregulates PubMed
    ribosome-binding protein 1 isoform 2 RRBP1 upregulates PubMed
    S-adenosylmethionine-dependent nucleotide dehydratase RSAD2 isoform 1 RSAD2 upregulates PubMed
    reticulon-4 isoform C RTN4 downregulates PubMed
    protein S100-B S100B upregulates PubMed
    secretory carrier-associated membrane protein 3 isoform 1 SCAMP3 upregulates PubMed
    scavenger receptor class A member 3 isoform 1 SCARA3 downregulates PubMed
    lysosome membrane protein 2 isoform 1 SCARB2 downregulates PubMed
    succinate dehydrogenase SDHA downregulates PubMed
    stress-associated endoplasmic reticulum protein 1 SERP1 downregulates PubMed
    plasminogen activator inhibitor 2 SERPINB2 downregulates PubMed
    plasminogen activator inhibitor 1 isoform 2 precursor SERPINE1 downregulates PubMed
    splicing factor 3B subunit 2 SF3B2 inhibits PubMed
    SF3B2 binds PubMed
    SF3B2 interacts with PubMed
    splicing factor 3B subunit 4 SF3B4 inhibits PubMed
    SF3B4 inhibits PubMed
    shugoshin 1 isoform 1KL SGO1 relocalizes PubMed
    SGO1 inhibits PubMed
    electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial SLC25A12 downregulates PubMed
    ADP/ATP translocase 1 SLC25A4 binds PubMed
    SLC25A4 binds PubMed
    SLC25A4 binds PubMed
    ADP/ATP translocase 2 SLC25A5 downregulates PubMed
    sodium/hydrogen exchanger 1 SLC9A1 downregulates PubMed
    SLC9A1 downregulates PubMed
    structure-specific endonuclease subunit SLX4 SLX4 interacts with PubMed
    SLX4 regulates PubMed
    SLX4 activates PubMed
    SLX4 activates PubMed
    SLX4 interacts with PubMed
    SLX4 complexes with PubMed
    protein SLX4IP SLX4IP interacts with PubMed
    mothers against decapentaplegic homolog 3 isoform 1 SMAD3 activates PubMed
    SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 SMARCA5 binds PubMed
    structural maintenance of chromosomes protein 1A isoform 1 SMC1A downregulates PubMed
    structural maintenance of chromosomes protein 1B isoform 1 SMC1B downregulates PubMed
    structural maintenance of chromosomes protein 3 SMC3 downregulates PubMed
    survival motor neuron protein isoform d SMN1 downregulates PubMed
    single-strand selective monofunctional uracil DNA glycosylase isoform 1 SMUG1 downregulates PubMed
    SMUG1 downregulates PubMed
    SMUG1 complexes with PubMed
    small nuclear ribonucleoprotein-associated protein N isoform b SNRPN interacts with PubMed
    sorbin and SH3 domain-containing protein 2 isoform 2 SORBS2 upregulates PubMed
    transcription factor Sp1 isoform a SP1 cooperates with PubMed
    SP1 cooperates with PubMed
    SP1 interacts with PubMed
    SP1 interacts with PubMed
    leukosialin precursor SPN antagonizes PubMed
    spectrin alpha chain, non-erythrocytic 1 isoform 1 SPTAN1 upregulates PubMed
    spectrin beta chain, non-erythrocytic 1 isoform 1 SPTBN1 co-localizes with PubMed
    sulfide:quinone oxidoreductase, mitochondrial SQOR upregulates PubMed
    lupus La protein SSB downregulates PubMed
    signal transducer and activator of transcription 1-alpha/beta isoform alpha STAT1 induces phosphorylation of PubMed
    STAT1 activates PubMed
    stimulator of interferon genes protein isoform 1 STING1 antagonizes PubMed
    stomatin-like protein 2, mitochondrial isoform a STOML2 downregulates PubMed
    succinate--CoA ligase SUCLG1 downregulates PubMed
    histone-lysine N-methyltransferase SUV39H1 isoform 2 SUV39H1 inhibited by PubMed
    TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 isoform 1 TAB3 interacts with PubMed
    transgelin-2 isoform b TAGLN2 upregulates PubMed
    serine/threonine-protein kinase TBK1 TBK1 interacts with PubMed
    TATA-box-binding protein isoform 1 TBP binds PubMed
    transcription factor 12 isoform d TCF12 downregulates PubMed
    telomerase reverse transcriptase isoform 1 TERT downregulates PubMed
    TERT downregulates PubMed
    tesmin isoform a TESMIN downregulates PubMed
    transferrin receptor protein 1 isoform 1 TFRC upregulates PubMed
    transforming growth factor beta-1 proprotein preproprotein TGFB1 modulates PubMed
    thrombospondin-1 precursor THBS1 stimulates PubMed
    metalloproteinase inhibitor 1 precursor TIMP1 upregulates PubMed
    thymidine kinase, cytosolic isoform 1 TK1 upregulates PubMed
    transketolase isoform 1 TKT downregulates PubMed
    toll-like receptor 4 isoform A precursor TLR4 cooperates with PubMed
    TLR4 downregulates PubMed
    transmembrane protein 11, mitochondrial TMEM11 interacts with PubMed
    transmembrane protein 160 precursor TMEM160 interacts with PubMed
    transmembrane protein 33 TMEM33 upregulates PubMed
    tumor necrosis factor TNF enhances PubMed
    TNF upregulates PubMed
    TNF cooperates with PubMed
    TNF inhibits PubMed
    TNF upregulates PubMed
    TNF inhibits PubMed
    TNF modulates PubMed
    tumor necrosis factor ligand superfamily member 10 isoform 1 TNFSF10 upregulates PubMed
    tumor necrosis factor ligand superfamily member 11 isoform 1 TNFSF11 upregulates PubMed
    tumor necrosis factor ligand superfamily member 15 isoform VEGI-192 TNFSF15 upregulates PubMed
    tumor necrosis factor ligand superfamily member 9 TNFSF9 upregulates PubMed
    transportin-1 isoform 1 TNPO1 interacts with PubMed
    TNPO1 regulates PubMed
    mitochondrial import receptor subunit TOM22 homolog TOMM22 downregulates PubMed
    cellular tumor antigen p53 isoform a TP53 interacts with PubMed
    TP53 upregulates PubMed
    TP53 upregulates PubMed
    TP53 upregulates PubMed
    TP53 inhibits PubMed
    TP53 interacts with PubMed
    TP53 regulated by PubMed
    TP53 activates PubMed
    TP53 inhibits PubMed
    TP53-binding protein 1 isoform 3 TP53BP1 interacts with PubMed
    TP53BP1 co-localizes with PubMed
    triosephosphate isomerase isoform 1 TPI1 downregulates PubMed
    transformer-2 protein homolog alpha isoform 1 TRA2A activated by PubMed
    transformer-2 protein homolog beta isoform 1 TRA2B activated by PubMed
    TNF receptor-associated factor 1 isoform a TRAF1 mediated by PubMed
    TNF receptor-associated factor 2 TRAF2 mediated by PubMed
    TNF receptor-associated factor 6 TRAF6 interacts with PubMed
    TRAF6 interacts with PubMed
    E3 ubiquitin-protein ligase TRIM11 TRIM11 regulates PubMed
    transient receptor potential cation channel subfamily V member 2 TRPV2 upregulates PubMed
    tumor susceptibility gene 101 protein TSG101 competes with PubMed
    TSG101 abrogates PubMed
    testis-specific Y-encoded-like protein 1 TSPYL1 interacts with PubMed
    tubulin beta-3 chain isoform 1 TUBB3 downregulates PubMed
    tubulin gamma-1 chain TUBG1 induces accumulation of PubMed
    tubulin gamma-2 chain isoform 2 TUBG2 induces accumulation of PubMed
    tubby-related protein 3 isoform 1 TULP3 interacts with PubMed
    thioredoxin-interacting protein isoform 2 TXNIP upregulates PubMed
    ubiquitin-ribosomal protein eL40 fusion protein isoform 1 precursor UBA52 upregulates PubMed
    ubiquitin-associated protein 2-like isoform a UBAP2L upregulates PubMed
    polyubiquitin-B precursor UBB complexes with PubMed
    UBB cooperates with PubMed
    polyubiquitin-C UBC complexes with PubMed
    UBC cooperates with PubMed
    ubiquitin D UBD co-localizes with PubMed
    UBD upregulates PubMed
    E3 ubiquitin-protein ligase UBR1 UBR1 induces complex with PubMed
    E3 ubiquitin-protein ligase UBR2 isoform 1 UBR2 complexes with PubMed
    E3 ubiquitin-protein ligase UBR3 UBR3 complexes with PubMed
    E3 ubiquitin-protein ligase UBR4 UBR4 complexes with PubMed
    E3 ubiquitin-protein ligase UBR5 isoform 1 UBR5 interacts with PubMed
    UBR5 complexes with PubMed
    UL16-binding protein 1 isoform 1 precursor ULBP1 upregulates PubMed
    ULBP1 upregulates PubMed
    ULBP1 upregulates PubMed
    ULBP1 upregulates PubMed
    ULBP1 upregulates PubMed
    UL16-binding protein 2 preproprotein ULBP2 upregulates PubMed
    ULBP2 upregulates PubMed
    ULBP2 upregulates PubMed
    ULBP2 upregulates PubMed
    ULBP2 upregulates PubMed
    ULBP2 upregulates PubMed
    ULBP2 upregulates PubMed
    UL16-binding protein 3 ULBP3 upregulates PubMed
    ULBP3 upregulates PubMed
    ULBP3 upregulates PubMed
    ULBP3 upregulates PubMed
    uracil-DNA glycosylase isoform UNG2 UNG inhibits PubMed
    UNG mimics DNA binding to PubMed
    UNG depletes PubMed
    UNG targets PubMed
    UNG binds PubMed
    UNG downregulates PubMed
    UNG downregulates PubMed
    UNG complexes with PubMed
    UNG induces ubiquitination of PubMed
    UNG degrades PubMed
    UNG degrades PubMed
    UNG degrades PubMed
    UNG binds PubMed
    UNG downregulates PubMed
    UNG complexes with PubMed
    UNG binds PubMed
    UNG induces phosphorylation of PubMed
    UNG activates PubMed
    UNG interacts with PubMed
    UNG binds PubMed
    UNG incorporates PubMed
    UNG induces ubiquitination of PubMed
    UNG incorporates PubMed
    UNG binds PubMed
    general vesicular transport factor p115 isoform 2 USO1 upregulates PubMed
    ubl carboxyl-terminal hydrolase 18 USP18 upregulates PubMed
    synaptic vesicle membrane protein VAT-1 homolog VAT1 upregulates PubMed
    voltage-dependent anion-selective channel protein 1 isoform 1 VDAC1 downregulates PubMed
    VDAC1 interacts with PubMed
    VDAC1 interacts with PubMed
    voltage-dependent anion-selective channel protein 2 isoform 2 VDAC2 downregulates PubMed
    VDAC2 interacts with PubMed
    voltage-dependent anion-selective channel protein 3 isoform 1 VDAC3 interacts with PubMed
    vimentin VIM downregulates PubMed
    VIM modulates PubMed
    wee1-like protein kinase isoform 1 WEE1 downregulates PubMed
    WEE1 binds PubMed
    WEE1 upregulates PubMed
    WEE1 interacts with PubMed
    WEE1 inhibited by PubMed
    WEE1 induces release of PubMed
    XIAP-associated factor 1 isoform 1 XAF1 upregulates PubMed
    exportin-1 isoform 1 XPO1 exported by PubMed
    XPO1 exported by PubMed
    14-3-3 protein beta/alpha YWHAB inhibits PubMed
    YWHAB enhanced by PubMed
    14-3-3 protein epsilon YWHAE inhibits PubMed
    YWHAE enhanced by PubMed
    14-3-3 protein gamma YWHAG inhibits PubMed
    YWHAG inhibits PubMed
    YWHAG enhanced by PubMed
    14-3-3 protein eta YWHAH inhibits PubMed
    YWHAH complexes with PubMed
    YWHAH binds PubMed
    YWHAH enhanced by PubMed
    14-3-3 protein theta YWHAQ interacts with PubMed
    YWHAQ inhibits PubMed
    YWHAQ binds PubMed
    14-3-3 protein zeta/delta YWHAZ interacts with PubMed
    YWHAZ inhibits PubMed
    YWHAZ enhanced by PubMed
    Z-DNA-binding protein 1 isoform b ZBP1 upregulates PubMed
    zinc finger CCCH-type with G patch domain-containing protein isoform a ZGPAT degrades PubMed
    ZGPAT complexes with PubMed
    zinc finger protein 512 isoform a ZNF512 downregulates PubMed
    zinc finger-containing ubiquitin peptidase 1 isoform 1 ZUP1 downregulates PubMed

    Go to the HIV-1, Human Interaction Database

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    General protein information

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    Preferred Names
    Vpr
    NP_057852.2
    • An artificial frameshift eliminating the orf-disrupting nucleotide at position 5320 is introduced to obtain the typical HIV-1 Vpr protein sequence. For this particular HIV-1 strain, HXB2, only a short (78 amino acid long) variant of the Vpr sequence can be obtained by translation of nucleotides 5105 through 5341 without the frameshift

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001802.1 Reference assembly

      Range
      5105..5396
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_057852.2 Vpr [Human immunodeficiency virus 1]

      See identical proteins and their annotated locations for NP_057852.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P05928, P69726
      Conserved Domains (1) summary
      pfam00522
      Location:1 → 82
      VPR; VPR/VPX protein
    Nucleotide Protein
    Heading Accession and Version

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