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| Status |
Public on Aug 22, 2016 |
| Title |
The tissue is the issue: Improved methylome analysis from paraffin-embedded tissues by application of the HOPE-technique |
| Organism |
Homo sapiens |
| Experiment type |
Methylation profiling by array
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| Summary |
Genome wide DNA methylation profiling of DNA samples obtained from normal lung tissue and lung carcinoma, either fixed by formalin (FFPE), HOPE (paraffin embedded) or cryo-preserved. Illumina's HumanMethylation450 BeadChip was used to obtain DNA methylation profiles across approximately 450.000 CpGs.
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| Overall design |
Bisulphite converted DNA from the 36 samples were hybridized to the Illumina HumanMethylation450 Beadchip.
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| Contributor(s) |
Ammerpohl O, Goldmann T |
| Citation(s) |
24933424 |
| Submission date |
Sep 23, 2013 |
| Last update date |
Mar 22, 2019 |
| Contact name |
Ole Ammerpohl |
| Organization name |
UK Ulm
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| Street address |
Albert-Einstein-Allee 11
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| City |
Ulm |
| ZIP/Postal code |
89081 |
| Country |
Germany |
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| Platforms (1) |
| GPL13534 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482) |
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| Samples (36)
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| GSM1237743 |
normal lung, cryo-preserved (15136) |
| GSM1237744 |
normal lung, formalin fixed, paraffin embedded (15136) |
| GSM1237745 |
normal lung, HOPE fixed, paraffin embedded (15136) |
| GSM1237746 |
lung carcinoma, cryo-preserved (15136) |
| GSM1237747 |
lung carcinoma, formalin fixed, paraffin embedded (15136) |
| GSM1237748 |
lung carcinoma, HOPE fixed, paraffin embedded (15136) |
| GSM1237749 |
normal lung, cryo-preserved (15343) |
| GSM1237750 |
normal lung, formalin fixed, paraffin embedded (15343) |
| GSM1237751 |
normal lung, HOPE fixed, paraffin embedded (15343) |
| GSM1237752 |
lung carcinoma, cryo-preserved (15343) |
| GSM1237753 |
lung carcinoma, formalin fixed, paraffin embedded (15343) |
| GSM1237754 |
lung carcinoma, HOPE fixed, paraffin embedded (15343) |
| GSM1237755 |
normal lung, cryo-preserved (15724) |
| GSM1237756 |
normal lung, formalin fixed, paraffin embedded (15724) |
| GSM1237757 |
normal lung, HOPE fixed, paraffin embedded (15724) |
| GSM1237758 |
lung carcinoma, cryo-preserved (15724) |
| GSM1237759 |
lung carcinoma, formalin fixed, paraffin embedded (15724) |
| GSM1237760 |
lung carcinoma, HOPE fixed, paraffin embedded (15724) |
| GSM1237761 |
normal lung, cryo-preserved (15725) |
| GSM1237762 |
normal lung, formalin fixed, paraffin embedded (15725) |
| GSM1237763 |
normal lung, HOPE fixed, paraffin embedded (15725) |
| GSM1237764 |
lung carcinoma, cryo-preserved (15725) |
| GSM1237765 |
lung carcinoma, formalin fixed, paraffin embedded (15725) |
| GSM1237766 |
lung carcinoma, HOPE fixed, paraffin embedded (15725) |
| GSM1237767 |
normal lung, cryo-preserved (5285) |
| GSM1237768 |
normal lung, formalin fixed, paraffin embedded (5285) |
| GSM1237769 |
normal lung, HOPE fixed, paraffin embedded (5285) |
| GSM1237770 |
lung carcinoma, cryo-preserved (5285) |
| GSM1237771 |
lung carcinoma, formalin fixed, paraffin embedded (5285) |
| GSM1237772 |
lung carcinoma, HOPE fixed, paraffin embedded (5285) |
| GSM1237773 |
normal lung, cryo-preserved (5770) |
| GSM1237774 |
normal lung, formalin fixed, paraffin embedded (5770) |
| GSM1237775 |
normal lung, HOPE fixed, paraffin embedded (5770) |
| GSM1237776 |
lung carcinoma, cryo-preserved (5770) |
| GSM1237777 |
lung carcinoma, formalin fixed, paraffin embedded (5770) |
| GSM1237778 |
lung carcinoma, HOPE fixed, paraffin embedded (5770) |
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| Relations |
| BioProject |
PRJNA221136 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE51077_RAW.tar |
183.1 Mb |
(http)(custom) |
TAR |
| GSE51077_signal_intensities.txt.gz |
149.2 Mb |
(ftp)(http) |
TXT |
| Processed data included within Sample table |
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