GEO DataSets

(Submitter supplied) Chemical warfare nerve agents (CWNA) are potent cholinesterase inhibitors that may also have non-cholinesterase effects. Several in vivo studies have shown that exposure to CWNA compounds induces damage in the brain and heart. Underlying mechanisms of this damage are a critical area of research for the development of medical countermeasures. This study utilized microRNA (miRNA) analysis to evaluate potential direct cellular effects of the nerve agent VX (o-ethyl-s-[2 (diisopropylamino) ethyl] methylphosphonothiolate) on human-induced pluripotent stem cell (iPSC)-derived neurons

Organism:

synthetic construct; Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL14613

24 Samples

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(Submitter supplied) #%create_date=Wed Dec 22 13:03:44 PST 2010 #%guid=04795ed5-9038-4dff-957e-da346791f552 #%chip_type=miRNA-2_0 # File order is all miRNAs that have mapping information grouped by organism, then all miRNAs without mapping information grouped by organism, then all sno/sca from UCSC and ensembl, and lastly the controls. # miRNAs: # An annot name generally represents one genome location," but may refer to multiple annotations because of multiple mature products delineated by ""-3p"" and ""-5p"""," or "".1"" and "".2""." # Also, those with a '*' are minor products, and those without '*' or any other aforementioned suffix are considered the major product. more...

Organism:

synthetic construct

187 Series

3459 Samples

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