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Items: 14

1.

Elucidating a normal function of huntingtin by analysis of huntingtin-null mouse embryonic fibroblasts

(Submitter supplied) The polyglutamine expansion in huntingtin (Htt) protein is a cause of Huntington’s disease (HD). Htt is an essential gene as deletion of the mouse Htt gene homolog (Hdh) is embryonic lethal in mice. Therefore, in addition to elucidating the mechanisms responsible for polyQ-mediated pathology, it is also important to understand the normal function of Htt protein for both basic biology and for HD. To systematically search for a mouse Htt function, we took advantage of the Hdh +/- and Hdh-floxed mice and generated four mouse embryonic fibroblast (MEF) cells lines which contain a single copy of the Hdh gene (Hdh-HET) and four MEF lines in which the Hdh gene was deleted (Hdh-KO). more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6731
12 Samples
Download data: TXT
Series
Accession:
GSE11139
ID:
200011139

PubMed Full text in PMC Similar studies Analyze with GEO2R

2.

Sentrix Mouse-6 Expression BeadChip (2)

(Submitter supplied) see manufacturer's website
Organism:
Mus musculus
1 Series
12 Samples
Download data
Platform
Accession:
GPL6731
ID:
100006731

3.

Hdh-KO-27 replicate2

Organism:
Mus musculus
Source name:
MEF cells
Platform:
GPL6731
Series:
GSE11139
Download data
Sample
Accession:
GSM281150
ID:
300281150

4.

Hdh-HET-5 replicate2

Organism:
Mus musculus
Source name:
MEF cells
Platform:
GPL6731
Series:
GSE11139
Download data
Sample
Accession:
GSM281149
ID:
300281149

5.

Hdh-KO-27 replicate1

Organism:
Mus musculus
Source name:
MEF cells
Platform:
GPL6731
Series:
GSE11139
Download data
Sample
Accession:
GSM281148
ID:
300281148

6.

Hdh-HET-5 replicate1

Organism:
Mus musculus
Source name:
MEF cells
Platform:
GPL6731
Series:
GSE11139
Download data
Sample
Accession:
GSM281147
ID:
300281147

7.

Hdh-KO-16 replicate2

Organism:
Mus musculus
Source name:
MEF cells
Platform:
GPL6731
Series:
GSE11139
Download data
Sample
Accession:
GSM281146
ID:
300281146

8.

Hdh-HET-3

Organism:
Mus musculus
Source name:
MEF cells
Platform:
GPL6731
Series:
GSE11139
Download data
Sample
Accession:
GSM281145
ID:
300281145

9.

Hdh-KO-16 replicate1

Organism:
Mus musculus
Source name:
MEF cells
Platform:
GPL6731
Series:
GSE11139
Download data
Sample
Accession:
GSM281144
ID:
300281144

10.

Hdh-HET-2 replicate2

Organism:
Mus musculus
Source name:
MEF cells
Platform:
GPL6731
Series:
GSE11139
Download data
Sample
Accession:
GSM281143
ID:
300281143

11.

Hdh-KO-12

Organism:
Mus musculus
Source name:
MEF cells
Platform:
GPL6731
Series:
GSE11139
Download data
Sample
Accession:
GSM281142
ID:
300281142

12.

Hdh-HET-2 replicate1

Organism:
Mus musculus
Source name:
MEF cells
Platform:
GPL6731
Series:
GSE11139
Download data
Sample
Accession:
GSM281141
ID:
300281141

13.

Hdh-KO-11

Organism:
Mus musculus
Source name:
MEF cells
Platform:
GPL6731
Series:
GSE11139
Download data
Sample
Accession:
GSM281140
ID:
300281140

14.

Hdh-HET-1

Organism:
Mus musculus
Source name:
MEF cells
Platform:
GPL6731
Series:
GSE11139
Download data
Sample
Accession:
GSM281139
ID:
300281139

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