tissue: adult brain disease state: normal (control)
Extracted molecule
genomic DNA
Extraction protocol
genomic DNA was extracted and purified from LBC samples using Qiagen DNeasy Kit according to standard instructions
Label
Cy5 and Cy3
Label protocol
Standard Illumina Protocol
Hybridization protocol
bisulphite converted DNA was amplified, fragmented and hybridised to Illumina Infinium Human Methylation450k Beadchip using standard Illumina protocol
Scan protocol
Arrays were imaged using BeadArray Reader using standard recommended Illumina scanner setting
Description
normal brain sample f2
Data processing
We removed probes with missing values, binding multiple genomic regions, binding targets with known sequence variants (1000 Genomes Project, SNPs with a minor allele frequency ≥ 2/120), or being located on the X or Y chromosomes. The final set contains 309,015 probes