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Status |
Public on Mar 31, 2013 |
Title |
Molar and incisor development |
Organism |
Mus musculus |
Experiment type |
Expression profiling by array
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Summary |
One of the key questions in developmental biology is how from universally shared molecular mechanisms and pathways, is it possible to generate organs displaying similar or complementary functions, with a wide range of different shapes or tissue organization? The dentition represents a valuable system to address the issues of differential molecular signatures generating specific tooth types. We performed a comparative transcriptomic analysis of developing murine lower incisors, mandibular molars and maxillary molars at the developmental cap stage (E14.5) prior to recognizable tooth shape and cusp pattern.
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Overall design |
We compared gene expression profiles in developing murine lower incisor and molars, as well as between the lower and upper (mandibular and maxillary) first molars
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Contributor(s) |
Laugel-Haushalter V, Paschaki M, Thibault-Carpentier C, Dembélé D, Dollé P, Bloch-Zupan A |
Citation(s) |
23531410 |
Submission date |
Dec 26, 2012 |
Last update date |
Mar 04, 2019 |
Contact name |
Doulaye Dembele |
E-mail(s) |
doulaye@igbmc.fr
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Phone |
+33 3 88 65 35 28
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Organization name |
IGBMC
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Department |
Biopuces
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Street address |
1 rue Laurent Fries
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City |
Illkirch |
ZIP/Postal code |
67400 |
Country |
France |
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Platforms (1) |
GPL6246 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version] |
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Samples (16)
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Relations |
BioProject |
PRJNA184720 |