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Series GSE42921 Query DataSets for GSE42921
Status Public on Jan 01, 2015
Title DNA methylation in a validation cohort of colon mucosa samples from individuals with Crohns' disease or ulcerative colitis and normal controls
Organism Homo sapiens
Experiment type Methylation profiling by genome tiling array
Summary Genome wide DNA methylation profiling of Crohn's disease, ulcerative colitis, and normal colon mucosa samples. The Illumina Infinium HumanMethylation450 BeadChip v1.1 was used to obtain DNA methylation profiles across 482,421 CpGs in colon mucosa samples. Samples came from 5 Crohn's disease affected, 5 ulcerative colitis affected, and 12 normal individuals. One ulcerative colitis sample was assayed before and after treatment with infliximab and mesalamine.
 
Overall design Bisulfite converted DNA from the 23 samples were hybridized to the Illumina Infinium HumanMethylation450 BeadChip v1.1
 
Contributor(s) Kellermayer R, Harris RA
Citation(s) 24937444
Submission date Dec 14, 2012
Last update date Mar 28, 2022
Contact name R. Alan Harris
E-mail(s) rharris1@bcm.edu
Organization name Baylor College of Medicine
Department Molecular and Human Genetics
Street address 1 Baylor Plaza
City Houston
State/province TX
ZIP/Postal code 77030
Country USA
 
Platforms (1)
GPL13534 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482)
Samples (23)
GSM1053381 Methylation in colon mucosa 421
GSM1053382 Methylation in colon mucosa 434
GSM1053383 Methylation in colon mucosa 422
Relations
BioProject PRJNA183877

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE42921_RAW.tar 183.1 Mb (http)(custom) TAR
GSE42921_RKMTIB_Norm_and_non-Norm_FinalReport.txt.gz 132.7 Mb (ftp)(http) TXT
Processed data included within Sample table
Processed data are available on Series record
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