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| Status |
Public on Nov 18, 2022 |
| Title |
N-Acetyl-L-cysteine facilitates tendon repair and promotes the tenogenic differentiation of tendon stem/progenitor cells by enhancing the integrin α5/β1/PI3K/AKT signaling |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
N-acetyl-L-cysteine (NAC) is a potent antioxidant. However, how NAC affects the biological functions of tendon stem/progenitor cells (TSPCs) and tendon repair has not been clarified.The effect of NAC on gene transcription in TSPCs was analyzed by transcriptomes and bioinformatics.
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| Overall design |
We then performed gene expression bioinformatics analysis using data obtained from RNA-seq of 2 group different cells after 7 days culturing.
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| Contributor(s) |
Lu K, Zhou M, Wang L, Wang Y, Tang H, Wang H, Tang C, He J, Wang W, Tang K, Wang Y, Deng Z |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Nov 15, 2022 |
| Last update date |
Nov 18, 2022 |
| Contact name |
Kang Lu |
| E-mail(s) |
lukang306656@hospital.cqmu.edu.cn
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| Phone |
18223936353
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| Organization name |
The Second Affiliated Hospital of Chongqing Medical University
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| Street address |
Gaotanyanzheng street
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| City |
Chongqing |
| ZIP/Postal code |
400030 |
| Country |
China |
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| Platforms (1) |
| GPL18694 |
Illumina HiSeq 2500 (Rattus norvegicus) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA901966 |
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