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| Status |
Public on Sep 15, 2020 |
| Title |
Effect of Idelalisib in follicular lymphoma monocultures and cocultured with follicular dendritic cells (FDC) |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Follicular Lymphoma primary cells (FL) were treated with the PI3K delta inhibitor idelalisib (500nM, 48h) in the presence or absence of follicular dendritic cells
We used microarrays to uncover the mechanisms underlying mechanism of resistance and sensitivity of FL to idelalisib
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| |
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| Overall design |
Global RNA expression was done in five primary FL biopsies treated in vitro with idelalisib in monoculture or cocultured with follicular dendritic cells
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| |
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| Contributor(s) |
Aymerich NS, Guerrero-Hernández M, Matas-Céspedes A, Pérez-Galán P |
| Citation(s) |
32898249 |
| Submission date |
May 08, 2019 |
| Last update date |
Sep 15, 2020 |
| Contact name |
Patricia Pérez-Galán |
| E-mail(s) |
pperez@clinic.cat
|
| Phone |
932275400
|
| Organization name |
IDIBAPS
|
| Department |
Hemato-oncology
|
| Street address |
Centre Esther Koplowitz, Hemato-oncology dept, Rosello 149-153, 2nd floor
|
| City |
Barcelona |
| State/province |
Barcelona |
| ZIP/Postal code |
08036 |
| Country |
Spain |
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| Platforms (1) |
| GPL13667 |
[HG-U219] Affymetrix Human Genome U219 Array |
|
| Samples (20)
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| Relations |
| BioProject |
PRJNA541941 |
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