U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    Zscan20 zinc finger and SCAN domains 20 [ Mus musculus (house mouse) ]

    Gene ID: 269585, updated on 5-Mar-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Zscan20provided by MGI
    Official Full Name
    zinc finger and SCAN domains 20provided by MGI
    Primary source
    MGI:MGI:2679268
    See related
    Ensembl:ENSMUSG00000061894 AllianceGenome:MGI:2679268
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Zfp31; Zkscan20; C130001F22
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in several structures, including cerebral cortex; early conceptus; ganglia; genitourinary system; and lung. Orthologous to human ZSCAN20 (zinc finger and SCAN domain containing 20). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in testis adult (RPKM 1.4), thymus adult (RPKM 1.2) and 28 other tissues See more
    Orthologs
    human all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Location:
    4 D2.2; 4 62.04 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (128472142..128503933, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (128578670..128610153, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene CUB and Sushi multiple domains 2 Neighboring gene high-mobility group box 4, opposite strand Neighboring gene STARR-seq mESC enhancer starr_11453 Neighboring gene predicted gene, 33656 Neighboring gene STARR-positive B cell enhancer ABC_E839 Neighboring gene STARR-seq mESC enhancer starr_11454 Neighboring gene predicted gene 12958 Neighboring gene toll-like receptor 12

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Guo G, et al. Dev Cell, 2010 Apr 20. PMID 20412781
    2. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article
    3. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
    4. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559
    5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Clone Names

    • MGC30798

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    zinc finger and SCAN domain-containing protein 20
    Names
    zinc finger protein 31
    zinc finger with KRAB and SCAN domains 20

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_177758.4 → NP_808426.2  zinc finger and SCAN domain-containing protein 20

      See identical proteins and their annotated locations for NP_808426.2

      Status: VALIDATED

      Source sequence(s)
      AK144249, BC065079, BC076602
      Consensus CDS
      CCDS18672.2
      UniProtKB/Swiss-Prot
      B1AS93, B2KFW1, Q3UNF0, Q6DFW6, Q8BJ07
      Related
      ENSMUSP00000095487.3, ENSMUST00000097877.9
      Conserved Domains (4) summary
      COG5048
      Location:686 → 1020
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:948 → 968
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam02023
      Location:41 → 126
      SCAN; SCAN domain
      pfam13837
      Location:476 → 561
      Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      128472142..128503933 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011240544.4 → XP_011238846.1  zinc finger and SCAN domain-containing protein 20 isoform X2

      Conserved Domains (4) summary
      COG5048
      Location:685 → 1019
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:947 → 967
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam02023
      Location:41 → 126
      SCAN; SCAN domain
      pfam13837
      Location:315 → 396
      Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

    2. XM_036164141.1 → XP_036020034.1  zinc finger and SCAN domain-containing protein 20 isoform X6

      Conserved Domains (3) summary
      COG5048
      Location:256 → 590
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:518 → 538
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13837
      Location:46 → 127
      Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

    3. XM_036164140.1 → XP_036020033.1  zinc finger and SCAN domain-containing protein 20 isoform X2

      Conserved Domains (4) summary
      COG5048
      Location:685 → 1019
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:947 → 967
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam02023
      Location:41 → 126
      SCAN; SCAN domain
      pfam13837
      Location:315 → 396
      Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

    4. XM_011240545.4 → XP_011238847.1  zinc finger and SCAN domain-containing protein 20 isoform X3

      Conserved Domains (4) summary
      COG5048
      Location:657 → 991
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:919 → 939
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13837
      Location:447 → 532
      Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain
      cl02605
      Location:29 → 104
      SCAN; SCAN oligomerization domain

    5. XM_011240542.4 → XP_011238844.1  zinc finger and SCAN domain-containing protein 20 isoform X1

      See identical proteins and their annotated locations for XP_011238844.1

      UniProtKB/Swiss-Prot
      B1AS93, B2KFW1, Q3UNF0, Q6DFW6, Q8BJ07
      Conserved Domains (4) summary
      COG5048
      Location:686 → 1020
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:948 → 968
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam02023
      Location:41 → 126
      SCAN; SCAN domain
      pfam13837
      Location:476 → 561
      Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

    6. XM_011240543.4 → XP_011238845.1  zinc finger and SCAN domain-containing protein 20 isoform X1

      See identical proteins and their annotated locations for XP_011238845.1

      UniProtKB/Swiss-Prot
      B1AS93, B2KFW1, Q3UNF0, Q6DFW6, Q8BJ07
      Conserved Domains (4) summary
      COG5048
      Location:686 → 1020
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:948 → 968
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam02023
      Location:41 → 126
      SCAN; SCAN domain
      pfam13837
      Location:476 → 561
      Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

    7. XM_011240546.4 → XP_011238848.1  zinc finger and SCAN domain-containing protein 20 isoform X4

      See identical proteins and their annotated locations for XP_011238848.1

      Conserved Domains (3) summary
      COG5048
      Location:505 → 839
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:767 → 787
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13837
      Location:295 → 380
      Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

    8. XM_011240547.4 → XP_011238849.1  zinc finger and SCAN domain-containing protein 20 isoform X5

      See identical proteins and their annotated locations for XP_011238849.1

      UniProtKB/Swiss-Prot
      B2KFW1
      Conserved Domains (3) summary
      COG5048
      Location:257 → 591
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:519 → 539
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13837
      Location:47 → 132
      Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

    9. XM_006503133.4 → XP_006503196.1  zinc finger and SCAN domain-containing protein 20 isoform X1

      See identical proteins and their annotated locations for XP_006503196.1

      UniProtKB/Swiss-Prot
      B1AS93, B2KFW1, Q3UNF0, Q6DFW6, Q8BJ07
      Conserved Domains (4) summary
      COG5048
      Location:686 → 1020
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:948 → 968
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam02023
      Location:41 → 126
      SCAN; SCAN domain
      pfam13837
      Location:476 → 561
      Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

    10. XM_006503131.3 → XP_006503194.1  zinc finger and SCAN domain-containing protein 20 isoform X1

      See identical proteins and their annotated locations for XP_006503194.1

      UniProtKB/Swiss-Prot
      B1AS93, B2KFW1, Q3UNF0, Q6DFW6, Q8BJ07
      Conserved Domains (4) summary
      COG5048
      Location:686 → 1020
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:948 → 968
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam02023
      Location:41 → 126
      SCAN; SCAN domain
      pfam13837
      Location:476 → 561
      Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

    11. XM_006503134.4 → XP_006503197.1  zinc finger and SCAN domain-containing protein 20 isoform X1

      See identical proteins and their annotated locations for XP_006503197.1

      UniProtKB/Swiss-Prot
      B1AS93, B2KFW1, Q3UNF0, Q6DFW6, Q8BJ07
      Conserved Domains (4) summary
      COG5048
      Location:686 → 1020
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:948 → 968
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam02023
      Location:41 → 126
      SCAN; SCAN domain
      pfam13837
      Location:476 → 561
      Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    B2KFW1.2 GenPept UniProtKB/Swiss-Prot:B2KFW1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous