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    Zmat4 zinc finger, matrin type 4 [ Mus musculus (house mouse) ]

    Gene ID: 320158, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Zmat4provided by MGI
    Official Full Name
    zinc finger, matrin type 4provided by MGI
    Primary source
    MGI:MGI:2443497
    See related
    Ensembl:ENSMUSG00000037492 AllianceGenome:MGI:2443497
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    9630048M01Rik
    Summary
    Predicted to enable identical protein binding activity. Predicted to be located in nucleus. Is expressed in jaw; nervous system; sensory organ; and urethra. Orthologous to human ZMAT4 (zinc finger matrin-type 4). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in cortex adult (RPKM 4.2), frontal lobe adult (RPKM 3.6) and 6 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    8 A2; 8 11.5 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (24137347..24553133)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (23647326..24063117)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene secreted frizzled-related protein 1 Neighboring gene RIKEN cDNA 4930413E20 gene Neighboring gene STARR-seq mESC enhancer starr_20923 Neighboring gene STARR-seq mESC enhancer starr_20924 Neighboring gene STARR-seq mESC enhancer starr_20925 Neighboring gene STARR-seq mESC enhancer starr_20926 Neighboring gene STARR-seq mESC enhancer starr_20927 Neighboring gene predicted gene, 30471 Neighboring gene STARR-seq mESC enhancer starr_20929 Neighboring gene STARR-seq mESC enhancer starr_20931 Neighboring gene STARR-seq mESC enhancer starr_20932 Neighboring gene STARR-seq mESC enhancer starr_20933 Neighboring gene predicted gene, 51564 Neighboring gene STARR-seq mESC enhancer starr_20934 Neighboring gene predicted gene, 57528 Neighboring gene STARR-seq mESC enhancer starr_20935 Neighboring gene STARR-seq mESC enhancer starr_20936 Neighboring gene predicted gene, 30633

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Sall1 balances self-renewal and differentiation of renal progenitor cells. Basta JM, et al. Development, 2014 Mar. PMID 24550112, Free PMC Article
    2. The treasury of the commons: making use of public gene expression resources to better characterize the molecular diversity of inhibitory interneurons in the cerebellar cortex. Schilling K, et al. Cerebellum, 2009 Dec. PMID 19554387
    3. Genomic analysis of mouse retinal development. Blackshaw S, et al. PLoS Biol, 2004 Sep. PMID 15226823, Free PMC Article
    4. A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Thompson CL, et al. Neuron, 2014 Jul 16. PMID 24952961, Free PMC Article
    5. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC90808

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger matrin-type protein 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001277239.1 → NP_001264168.1  zinc finger matrin-type protein 4 isoform 2

      See identical proteins and their annotated locations for NP_001264168.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) contains an alternate internal exon compared to variant 1, that causes translation to begin from a downstream AUG. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1.
      Source sequence(s)
      AK036254, AK140413, BC079657, BQ174274
      Consensus CDS
      CCDS85514.1
      UniProtKB/Swiss-Prot
      Q8BZ94
      Related
      ENSMUSP00000146734.2, ENSMUST00000207301.2
      Conserved Domains (3) summary
      smart00451
      Location:73 → 107
      ZnF_U1; U1-like zinc finger
      COG5246
      Location:96 → 160
      PRP11; Splicing factor 3a, subunit 2 [RNA processing and modification]
      sd00020
      Location:78 → 100
      ZF_C2H2; C2H2 Zn finger [structural motif]

    2. NM_177086.4 → NP_796060.1  zinc finger matrin-type protein 4 isoform 1

      See identical proteins and their annotated locations for NP_796060.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1).
      Source sequence(s)
      AK036254, AK140413, BQ174274
      Consensus CDS
      CCDS22192.1
      UniProtKB/Swiss-Prot
      Q3USG2, Q6AXC5, Q8BZ94
      Related
      ENSMUSP00000049430.5, ENSMUST00000042352.11
      Conserved Domains (3) summary
      smart00451
      Location:142 → 176
      ZnF_U1; U1-like zinc finger
      COG5246
      Location:165 → 229
      PRP11; Splicing factor 3a, subunit 2 [RNA processing and modification]
      sd00020
      Location:147 → 169
      ZF_C2H2; C2H2 Zn finger [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      24137347..24553133
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017312858.3 → XP_017168347.1  zinc finger matrin-type protein 4 isoform X2

      UniProtKB/Swiss-Prot
      Q3USG2, Q6AXC5, Q8BZ94
      Conserved Domains (3) summary
      smart00451
      Location:142 → 176
      ZnF_U1; U1-like zinc finger
      COG5246
      Location:165 → 229
      PRP11; Splicing factor 3a, subunit 2 [RNA processing and modification]
      sd00020
      Location:147 → 169
      ZF_C2H2; C2H2 Zn finger [structural motif]

    2. XM_006509141.3 → XP_006509204.1  zinc finger matrin-type protein 4 isoform X2

      See identical proteins and their annotated locations for XP_006509204.1

      UniProtKB/Swiss-Prot
      Q3USG2, Q6AXC5, Q8BZ94
      Conserved Domains (3) summary
      smart00451
      Location:142 → 176
      ZnF_U1; U1-like zinc finger
      COG5246
      Location:165 → 229
      PRP11; Splicing factor 3a, subunit 2 [RNA processing and modification]
      sd00020
      Location:147 → 169
      ZF_C2H2; C2H2 Zn finger [structural motif]

    3. XM_006509140.4 → XP_006509203.1  zinc finger matrin-type protein 4 isoform X2

      See identical proteins and their annotated locations for XP_006509203.1

      UniProtKB/Swiss-Prot
      Q3USG2, Q6AXC5, Q8BZ94
      Conserved Domains (3) summary
      smart00451
      Location:142 → 176
      ZnF_U1; U1-like zinc finger
      COG5246
      Location:165 → 229
      PRP11; Splicing factor 3a, subunit 2 [RNA processing and modification]
      sd00020
      Location:147 → 169
      ZF_C2H2; C2H2 Zn finger [structural motif]

    4. XM_030243610.1 → XP_030099470.1  zinc finger matrin-type protein 4 isoform X1

      Conserved Domains (3) summary
      smart00451
      Location:156 → 190
      ZnF_U1; U1-like zinc finger
      COG5246
      Location:179 → 243
      PRP11; Splicing factor 3a, subunit 2 [RNA processing and modification]
      sd00020
      Location:161 → 183
      ZF_C2H2; C2H2 Zn finger [structural motif]

    5. XM_011242142.3 → XP_011240444.1  zinc finger matrin-type protein 4 isoform X2

      See identical proteins and their annotated locations for XP_011240444.1

      UniProtKB/Swiss-Prot
      Q3USG2, Q6AXC5, Q8BZ94
      Conserved Domains (3) summary
      smart00451
      Location:142 → 176
      ZnF_U1; U1-like zinc finger
      COG5246
      Location:165 → 229
      PRP11; Splicing factor 3a, subunit 2 [RNA processing and modification]
      sd00020
      Location:147 → 169
      ZF_C2H2; C2H2 Zn finger [structural motif]

    6. XM_011242141.3 → XP_011240443.1  zinc finger matrin-type protein 4 isoform X2

      See identical proteins and their annotated locations for XP_011240443.1

      UniProtKB/Swiss-Prot
      Q3USG2, Q6AXC5, Q8BZ94
      Conserved Domains (3) summary
      smart00451
      Location:142 → 176
      ZnF_U1; U1-like zinc finger
      COG5246
      Location:165 → 229
      PRP11; Splicing factor 3a, subunit 2 [RNA processing and modification]
      sd00020
      Location:147 → 169
      ZF_C2H2; C2H2 Zn finger [structural motif]

    7. XM_006509139.5 → XP_006509202.1  zinc finger matrin-type protein 4 isoform X1

      Conserved Domains (3) summary
      smart00451
      Location:156 → 190
      ZnF_U1; U1-like zinc finger
      COG5246
      Location:179 → 243
      PRP11; Splicing factor 3a, subunit 2 [RNA processing and modification]
      sd00020
      Location:161 → 183
      ZF_C2H2; C2H2 Zn finger [structural motif]

    8. XM_030243611.2 → XP_030099471.1  zinc finger matrin-type protein 4 isoform X1

      Conserved Domains (3) summary
      smart00451
      Location:156 → 190
      ZnF_U1; U1-like zinc finger
      COG5246
      Location:179 → 243
      PRP11; Splicing factor 3a, subunit 2 [RNA processing and modification]
      sd00020
      Location:161 → 183
      ZF_C2H2; C2H2 Zn finger [structural motif]

    9. XM_006509142.5 → XP_006509205.1  zinc finger matrin-type protein 4 isoform X3

      Conserved Domains (3) summary
      smart00451
      Location:96 → 130
      ZnF_U1; U1-like zinc finger
      COG5246
      Location:119 → 183
      PRP11; Splicing factor 3a, subunit 2 [RNA processing and modification]
      sd00020
      Location:101 → 123
      ZF_C2H2; C2H2 Zn finger [structural motif]

    10. XM_030243612.2 → XP_030099472.1  zinc finger matrin-type protein 4 isoform X4

      Conserved Domains (3) summary
      smart00451
      Location:73 → 107
      ZnF_U1; U1-like zinc finger
      COG5246
      Location:96 → 160
      PRP11; Splicing factor 3a, subunit 2 [RNA processing and modification]
      sd00020
      Location:78 → 100
      ZF_C2H2; C2H2 Zn finger [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8BZ94.1 GenPept UniProtKB/Swiss-Prot:Q8BZ94

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