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Items: 4

1.

Genome-wide profiling of PARP1 reveals an interplay with gene regulatory regions and DNA methylation

(Submitter supplied) To address the global impact of PARP-1 on DNA methylation, we treated cells with PJ34 (PARylation inhibitor) and isolated genomic DNA from vehicle and PJ34 treated cells. This DNA was bisulfite treated and hybridized to the Illumina infinium Methylation 450 Beadchip. We next used these RNA-seq data sets (control, PARP-1 KD and PARylation inhibited) to assess whether PARP plays a role in DNA methylation by assessing differential methylation patterns. more...
Organism:
Homo sapiens
Type:
Methylation profiling by array
Platform:
GPL13534
2 Samples
Download data: TXT
Series
Accession:
GSE61744
ID:
200061744
2.

Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482)

(Submitter supplied) 1 difference between HumanMethylation450_15017482_v.1.1.bpm and HumanMethylation450_15017482_v.1.2.bpm: 1.1: 41636384,NEGATIVE,-99,Negative 604 1.2: 41636384,RESTORATION,Green,Restore Protocol: See manufacturer's website
Organism:
Homo sapiens
1671 Series
1 Related Platform
117793 Samples
Download data: BPM, CSV, TXT, XLSX
Platform
Accession:
GPL13534
ID:
100013534
3.

DNA methylation in NT cells

Organism:
Homo sapiens
Source name:
Breast cancer cell line
Platform:
GPL13534
Series:
GSE61744
Download data
Sample
Accession:
GSM1513283
ID:
301513283
4.

DNA-methylation in PJ-34 treated cells

Organism:
Homo sapiens
Source name:
Breast cancer cell line
Platform:
GPL13534
Series:
GSE61744
Download data
Sample
Accession:
GSM1513282
ID:
301513282
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Supplemental Content

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