GEO DataSets

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL2715

44 Samples

Download data: TXT

(Submitter supplied) We performed microarray-based expression profiling on liver of male zebrafish exposed to 30 µg/L of cadmium (II) chloride for 8-96 h, to identify global transcriptional programs and biological pathways involved in cadmium-induced adaptive responses under in vivo environment.

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL2715

22 Samples

Download data: TXT

(Submitter supplied) We performed microarray-based expression profiling on liver of female zebrafish exposed to 30 µg/L of cadmium (II) chloride for 8-96 h, to identify global transcriptional programs and biological pathways involved in cadmium-induced adaptive responses under in vivo environment.

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL2715

22 Samples

Download data: TXT

(Submitter supplied) We performed microarray-based expression profiling on liver of male zebrafish exposed to 15ppm (~ 192 µM) of arsenic [As(V)] for 8-96 h, to identify global transcriptional programs and biological pathways involved in chloroaniline-induced adaptive responses under in vivo environment.

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL2715

24 Samples

Download data: TXT

(Submitter supplied) We performed microarray-based expression profiling on liver of male zebrafish exposed to 7 mg/L of nitrophenol for 8-96 h, to identify global transcriptional programs and biological pathways involved in chloroaniline-induced adaptive responses under in vivo environment.

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL2715

24 Samples

Download data: TXT

(Submitter supplied) We performed microarray-based expression profiling on liver of male zebrafish exposed to 7 mg/L of nitrophenol for 8-96 h, to identify global transcriptional programs and biological pathways involved in chloroaniline-induced adaptive responses under in vivo environment.

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL2715

24 Samples

Download data: TXT

(Submitter supplied) We performed microarray-based expression profiling on liver of male zebrafish exposed to 30 µg/L of chloroaniline for 8-96 h, to identify global transcriptional programs and biological pathways involved in chloroaniline-induced adaptive responses under in vivo environment.

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL2715

24 Samples

Download data: TXT

(Submitter supplied) We performed microarray-based expression profiling on liver of male zebrafish exposed to 30 µg/L of chloroaniline for 8-96 h, to identify global transcriptional programs and biological pathways involved in chloroaniline-induced adaptive responses under in vivo environment.

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL2715

24 Samples

Download data: TXT

(Submitter supplied) We performed microarray experiment on zebrafish exposed to estrogen (17β-estradiol; a classified carcinogen) and an anti-estrogen (ICI 182,780). Our transcriptome analysis captured multiple estrogen-responsive genes and signaling pathways that increased cell proliferation, promoted DNA damage and genome instability, and decreased tumor suppressing effects, suggesting a common mechanism for estrogen-induced carcinogenesis. more...

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL2715

10 Samples

Download data: GPR, TXT

(Submitter supplied) Full title: Mercury-Induced Hepatotoxicity in Zebrafish: In Vivo Mechanistic Insights from Transcriptome Analysis, Phenotype Anchoring and Targeted Gene Expression Validation In this study, we performed microarray-based expression profiling on liver of zebrafish exposed to 200 µg/L of mercuric chloride for 8-96 h, to identify global transcriptional programs and biological pathways involved in mercury-induced adaptive responses under in vivo environment.

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL2715

24 Samples

Download data: TXT

(Submitter supplied) The Notch signaling is an evolutionarily conserved signal transduction cascade that plays essential roles in a variety of developmental processes. In this study, we examined the mib mutants for defects in pancreas development using in situ hybridization and GFP expression analysis of pancreas-specific GFP lines, and carried out the global gene expression profile analysis of three different mib mutantalleles. more...

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL2715

42 Samples

Download data

(Submitter supplied) In this study, we performed microarray-based expression profiling on liver of zebrafish exposed to 60 mg/L (192?M) arsenic [As(V)] for 8-96 h, to identify global transcriptional programs and biological networks involved in arsenic-induced adaptive responses in vivo. We identified temporal differentially-expressed gene sets which we have grouped into early, late and all-time arsenic-responsive gene sets. more...

Organism:

Danio rerio

Type:

Expression profiling by array

Dataset:

GDS2249

Platform:

GPL2715

24 Samples

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Analysis of livers of animals at various time points up to 96 hours following exposure to 15 ppm arsenic. Arsenic is an environmental toxicant and carcinogen. Results provide insight into the molecular mechanisms underlying the toxicity and carcinogenicity of arsenic.

Organism:

Danio rerio

Type:

Expression profiling by array, log2 ratio, 2 agent, 4 time sets

Platform:

GPL2715

Series:

GSE3048

24 Samples

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(Submitter supplied) Zebrafish has been advocated as a cancer model, but little is known about the molecular similarities between zebrafish and human tumors. Comparative analysis of microarray data from zebrafish liver tumors with those from four human tumor types revealed molecular conservation at various levels between fish and human tumors. This approach provides a useful strategy for identifying expression signature that is strongly associated with a disease phenotype. more...

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL2715

20 Samples

Download data

(Submitter supplied) This set includes 16416 oligo probes (60 mers) designed by Compugen-Sigma. Spotted long oligonucleotide array on glass Protocol: See GISMADB homepage

Organism:

Danio rerio

1 DataSet

13 Series

224 Samples

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