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| Status |
Public on Mar 31, 2010 |
| Title |
Mercury-Induced Hepatotoxicity in Zebrafish |
| Organism |
Danio rerio |
| Experiment type |
Expression profiling by array
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| Summary |
Full title: Mercury-Induced Hepatotoxicity in Zebrafish: In Vivo Mechanistic Insights from Transcriptome Analysis, Phenotype Anchoring and Targeted Gene Expression Validation
In this study, we performed microarray-based expression profiling on liver of zebrafish exposed to 200 µg/L of mercuric chloride for 8-96 h, to identify global transcriptional programs and biological pathways involved in mercury-induced adaptive responses under in vivo environment.
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| Overall design |
We analyzed 12 arrays for mercuric chloride treated zebrafish liver and 12 arrays for control liver.
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| Contributor(s) |
Ung CY, Lam SH, Winata C, Mathavan S, Gong Z |
| Citation(s) |
20353558 |
| Submission date |
Nov 03, 2009 |
| Last update date |
Mar 21, 2012 |
| Contact name |
Choong Yong UNG |
| Organization name |
National University of Singapore
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| Department |
Biological Sciences Department
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| Lab |
Gong Zhiyuan
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| Street address |
Science Drive 4
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| City |
Singapore |
| State/province |
Singapore |
| ZIP/Postal code |
117543 |
| Country |
Singapore |
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| Platforms (1) |
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| Samples (24)
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| GSM467501 |
Control at 24hr, 1 |
| GSM467502 |
Control at 24hr, 2 |
| GSM467503 |
Control at 24hr, 3 |
| GSM467504 |
Control at 48hr, 1 |
| GSM467505 |
Control at 48hr, 2 |
| GSM467506 |
Control at 48hr, 3 |
| GSM467507 |
Control at 96hr, 1 |
| GSM467508 |
Control at 96hr, 2 |
| GSM467509 |
Control at 96hr, 3 |
| GSM467510 |
Mercuric chloride treated for 8hr, 1 |
| GSM467511 |
Mercuric chloride treated for 8hr, 2 |
| GSM467512 |
Mercuric chloride treated for 8hr, 3 |
| GSM467513 |
Mercuric chloride treated for 24hr, 1 |
| GSM467514 |
Mercuric chloride treated for 24hr, 2 |
| GSM467515 |
Mercuric chloride treated for 24hr, 3 |
| GSM467516 |
Mercuric chloride treated for 48hr, 1 |
| GSM467517 |
Mercuric chloride treated for 48hr, 2 |
| GSM467518 |
Mercuric chloride treated for 48hr, 3 |
| GSM467519 |
Mercuric chloride treated for 96hr, 1 |
| GSM467520 |
Mercuric chloride treated for 96hr, 2 |
| GSM467521 |
Mercuric chloride treated for 96hr, 3 |
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| Relations |
| BioProject |
PRJNA121109 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE18861_RAW.tar |
18.4 Mb |
(http)(custom) |
TAR (of TXT) |
| Processed data included within Sample table |
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