rbp4l retinol binding protein 4, like [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: rbp4lprovided by ZNC
Official Full Name: retinol binding protein 4, likeprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-7591
See related: Ensembl:ENSDARG00000044684 AllianceGenome:ZFIN:ZDB-GENE-030131-7591
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:73163; wu:fk53a11
Summary: Predicted to enable retinol binding activity and retinol transmembrane transporter activity. Acts upstream of or within retina development in camera-type eye. Is expressed in neural crest; visual system; and yolk syncytial layer. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 21

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	21	NC_007132.7 (20339689..20342022, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	21	NC_007132.6 (20303053..20305386, complement)

Chromosome 21 - NC_007132.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

These data strongly indicate that purpurin is a key molecule for the cell differentiation during early retinal development in zebrafish under transcriptional crx regulation.
Title: A hypoplastic retinal lamination in the purpurin knock down embryo in zebrafish.
These results strongly suggest that purpurin is a key molecule for not only optic nerve regeneration in adult but also cell differentiation during early development in embryo.
Title: Purpurin is a key molecule for cell differentiation during the early development of zebrafish retina.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables retinoid binding	IEA Inferred from Electronic Annotation more info
enables retinol binding	IEA Inferred from Electronic Annotation more info
enables retinol transmembrane transporter activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within retina development in camera-type eye	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular space	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: retinol binding protein 4, like

Names: purpurin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.