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Study Description

We used whole genome sequencing, RNA sequencing, and DNA methylation data resources on Framingham Heart Study participants to generate molecular resources of genotype vs. expression (eQTLs), genotype vs. DNA methylation (mQTLs), and DNA methylation vs. expression (eQTMs). 

The eQTL, mQTL, and eQTM papers have been published to MdRxiv:
mQTLs: medrxiv.org
eQTMs: medrxiv.org
eQTLs: medrxiv.org

Authorized Access
Publicly Available Data (Public ftp)
Study Inclusion/Exclusion Criteria

Exclusions: no whole genome sequencing, no RNA sequencing, no DNA methylation data (as appropriate); withdrawal of consent.

Study History

See parent study details: phs000007

Selected Publications
Diseases/Traits Related to Study (MeSH terms)
Links to Related Resources
Authorized Data Access Requests
See research articles citing use of the data from this study
Study Attribution
  • Principal Investigator
    • Daniel Levy. Population Sciences Branch, National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health, Framingham, MA, USA.
  • Co-Investigators
    • Roby Joehanes. Population Sciences Branch, National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health, Framingham, MA, USA.
    • Jiantao Ma. Friedman School of Nutrition, Tufts University, Boston, MA, USA.
    • Chunyu Liu. School of Public Health, Boston University, Boston, MA, USA.