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Parotid gland squamous cell carcinoma

MedGen UID:
233317
•Concept ID:
C1335367
•
Neoplastic Process
Synonyms: Parotid Gland Squamous Cell Carcinoma; parotid gland squamous cell carcinoma; Parotid Squamous Cell Carcinoma; parotid squamous cell carcinoma; Squamous Cell Carcinoma of Parotid; squamous cell carcinoma of parotid; Squamous Cell Carcinoma of Parotid Gland; squamous cell carcinoma of parotid gland; Squamous Cell Carcinoma of the Parotid; squamous cell carcinoma of the parotid; Squamous Cell Carcinoma of the Parotid Gland; squamous cell carcinoma of the parotid gland
 
Monarch Initiative: MONDO:0006358

Definition

An invasive squamous cell carcinoma that arises from the parotid gland. It usually affects elderly patients and presents as a rapidly enlarging tumor mass, often associated with pain. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVParotid gland squamous cell carcinoma

Professional guidelines

PubMed

Primary squamous cell carcinoma of the parotid gland: clinicopathological characteristics, treatment, and prognosis.
Xiao M, Liu J, You Y, Yang X, Wang Y
Int J Oral Maxillofac Surg 2021 Feb;50(2):151-157. Epub 2020 Jul 4 doi: 10.1016/j.ijom.2020.06.010. PMID: 32631631
Metastases to the parotid gland - A review of the clinicopathological evolution, molecular mechanisms and management.
Badlani J, Gupta R, Smith J, Ashford B, Ch'ng S, Veness M, Clark J
Surg Oncol 2018 Mar;27(1):44-53. Epub 2017 Dec 2 doi: 10.1016/j.suronc.2017.11.007. PMID: 29549903
Submandibular gland cancer: Specific features and treatment considerations.
Aro K, Tarkkanen J, Saat R, Saarilahti K, Mäkitie A, Atula T
Head Neck 2018 Jan;40(1):154-162. Epub 2017 Oct 30 doi: 10.1002/hed.24981. PMID: 29083518

Recent clinical studies

Etiology

The Heterogenicity of Parotid Gland Squamous Cell Carcinoma: A Study of 49 Patients.
Franzen A, Lieder A, Guenzel T, Buchali A
In Vivo 2019 Nov-Dec;33(6):2001-2006. doi: 10.21873/invivo.11696. PMID: 31662530Free PMC Article
Parotid gland squamous cell carcinoma invading the temporomandibular joint.
Klasser GD, Epstein JB, Utsman R, Yao M, Nguyen PH
J Am Dent Assoc 2009 Aug;140(8):992-9. doi: 10.14219/jada.archive.2009.0309. PMID: 19654251

Diagnosis

The Heterogenicity of Parotid Gland Squamous Cell Carcinoma: A Study of 49 Patients.
Franzen A, Lieder A, Guenzel T, Buchali A
In Vivo 2019 Nov-Dec;33(6):2001-2006. doi: 10.21873/invivo.11696. PMID: 31662530Free PMC Article
Parotid gland squamous cell carcinoma invading the temporomandibular joint.
Klasser GD, Epstein JB, Utsman R, Yao M, Nguyen PH
J Am Dent Assoc 2009 Aug;140(8):992-9. doi: 10.14219/jada.archive.2009.0309. PMID: 19654251

Prognosis

Parotid gland squamous cell carcinoma invading the temporomandibular joint.
Klasser GD, Epstein JB, Utsman R, Yao M, Nguyen PH
J Am Dent Assoc 2009 Aug;140(8):992-9. doi: 10.14219/jada.archive.2009.0309. PMID: 19654251

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