|
| Status |
Public on Oct 02, 2014 |
| Title |
Tumor Xenograft SGI-110 treated (rep2) |
| Sample type |
genomic |
| |
|
| Source name |
peritoneal tumor
|
| Organism |
Homo sapiens |
| Characteristics |
cell line: A2780
tumor type: ovarian cancer xenograft
treatment: demethylating agent SGI-110
|
| Growth protocol |
Peritoneal tumors xenografts were grown in athymic nude mice
|
| Extracted molecule |
genomic DNA |
| Extraction protocol |
Genomic DNA was extracted and purified from cells using Qiagen QiaAMP kit according to standard instructions.
|
| Label |
Cy5 and Cy3
|
| Label protocol |
Standard Infinium HD Methylation Assay Protocol
|
| |
|
| Hybridization protocol |
DNA was amplified, fragmented, and hybridized to Illumina Infinium HumanMethylation450 BeadChip using standard Infinium HD Methylation Assay protocol.
|
| Scan protocol |
Arrays were imaged with HiScan Reader using recommended Illumina scanner settings.
|
| Description |
Ovarian cancer xenografts grown in mice treated with carboplatin and then with SGI-110 during tumor recurrence.
|
| Data processing |
GenomeStudio v2011.2 with Methylation module v1.8.5
Unmethylated and methylated signal intensities
|
| |
|
| Submission date |
Mar 05, 2014 |
| Last update date |
Oct 02, 2014 |
| Contact name |
Horacio Cardenas |
| E-mail(s) |
horacard@iu.edu
|
| Phone |
317-274-7305
|
| Organization name |
Indiana University
|
| Street address |
980 West Walnut Street
|
| City |
Indianapolis |
| State/province |
IN |
| ZIP/Postal code |
46202 |
| Country |
USA |
| |
|
| Platform ID |
GPL13534 |
| Series (1) |
| GSE55613 |
Effects of SGI-110 on A2780 ovarian cancer xenografts |
|
