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| Status |
Public on Nov 10, 2007 |
| Title |
Primary nasal epithelium exposed to house dust mite extract shows activated expression in allergics |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Response to allergen was studied in epithelial cells derived from allergic pantients and from healthy controls. Cells were cultured after isolation from a nasal biopsy. Cells were exposed to Housed dust mite or vessel (saline)
Microarray data was analysed using bioinformatics and biostaistics. We conclude that a marked difference in basal expression and in response to hous dust mite exists
Keywords: cellular response to allergen
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| Overall design |
We used 5 monotypic house dust mite allergic patients and 5 non-allergic healthy controls, the cells obtained from the biopsies were cultured in two wells, for two different conditions.
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| Contributor(s) |
Vroling AB, Jonker MJ, Luiten S, Breit TM, Fokkens WJ, van Drunen CM |
| Citation(s) |
17901406 |
| Submission date |
Sep 24, 2007 |
| Last update date |
Mar 25, 2019 |
| Contact name |
Aram Ben Vroling |
| E-mail(s) |
aramvroling@hotmail.com
|
| Organization name |
AMC
|
| Department |
ENT
|
| Lab |
ENT
|
| Street address |
meibergdreef 9
|
| City |
Amsterdam |
| ZIP/Postal code |
1100DD |
| Country |
Netherlands |
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| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
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| Samples (20)
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| Relations |
| BioProject |
PRJNA102699 |
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