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Status |
Public on Jul 22, 2015 |
Title |
Genome-wide epigenetic cross-talk between DNA methylation and H3K27me3 in zebrafish embryos |
Organism |
Danio rerio |
Experiment type |
Genome binding/occupancy profiling by high throughput sequencing Methylation profiling by high throughput sequencing
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Summary |
DNA methylation and histone modifications are epigenetic marks implicated in the complex regulation of vertebrate embryogenesis. The cross-talk between DNA methylation and Polycomb-dependent H3K27me3 histone mark has been reported in a number of organisms and both marks are known to be required for proper developmental progression. Here we provide genome-wide DNA methylation (MethylCap-seq) and H3K27me3 (ChIP-seq) maps for three stages (dome, 24hpf and 48hpf) of zebrafish (Danio rerio) embryogenesis, as well as all analytical and methodological details associated with the generation of this dataset.
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Overall design |
DNA methylation (MethylCap-seq) and H3K27me3 (ChIP-seq) profling of zebrafish embryogenesis
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Contributor(s) |
Bogdanovic O |
Citation(s) |
26697317 |
Submission date |
Jul 13, 2015 |
Last update date |
May 15, 2019 |
Contact name |
Ozren Bogdanovic |
E-mail(s) |
o.bogdanovic@gmail.com
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Organization name |
Garvan Institute of Medical Research
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Department |
Genomics and Epigenetics
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Street address |
384 Victoria Street
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City |
Darlinghurst |
State/province |
NSW |
ZIP/Postal code |
2010 |
Country |
Australia |
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Platforms (1) |
GPL14875 |
Illumina HiSeq 2000 (Danio rerio) |
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Samples (5)
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Relations |
BioProject |
PRJNA289683 |
SRA |
SRP060753 |