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Status |
Public on Aug 17, 2015 |
Title |
The idiopathic preterm delivery methylation profile in umbilical cord blood |
Organism |
Homo sapiens |
Experiment type |
Methylation profiling by genome tiling array
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Summary |
Genome wide DNA methylation differences in umbilical cord blood (UCB) of preterm and term born neonates. The Illumina 450K Human DNA methylation Beadchip was used to obtain the DNA methylation profiles of 12 preterm and 12 term UCB samples across 450,000 CpGs. 2 samples were removed due to failed quality control, and BMIQ normalization was done with 11 preterm and 11 term samples.
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Overall design |
The bisulphite converted DNA of 12 preterm and 12 term samples was subjected to whole genome amplification, fragmentation followed by hybridization on Illumina 450K Human methylation bead chip array.
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Contributor(s) |
Fernando F, Keijser R, Henneman P, van der Kevie-Kersemaekers AF, Mul AN, Mannens MM, van der Post JA, Afink GB, Ris-Stalpers C |
Citation(s) |
26419829 |
Submission date |
Mar 03, 2015 |
Last update date |
Mar 22, 2019 |
Contact name |
Febilla Fernando |
E-mail(s) |
j.f.fernando@amc.nl
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Phone |
+31205661882
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Organization name |
Academic Medical Center
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Department |
Reproductive Biology Laboratory
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Street address |
Meibergdreef 9
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City |
Amsterdam |
ZIP/Postal code |
1105AZ |
Country |
Netherlands |
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Platforms (1) |
GPL13534 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482) |
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Samples (22)
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Relations |
BioProject |
PRJNA277013 |