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Series GSE64491 Query DataSets for GSE64491
Status Public on Jun 03, 2015
Title DNA methylation profiles of 30 tissues from a 112 year old woman
Organism Homo sapiens
Experiment type Methylation profiling by genome tiling array
Summary The main goal of the study was to measure the epigenetic age (also known as DNA methylation age) of these tissues. Toward this end, we used the epigenetic clock software described in Horvath S (n=2013) DNA methylation age of human tissues and cell types. Genome Biology.2013, 14:R115. DOI: 10.1186/10.1186/gb-2013-14-10-r115 PMID: 24138928
 
Overall design Human DNA methylation Beadchip v1.2 was used to obtain n=64 Illumina DNA methylation arrays from 30 tissues. For each of the following tissues, we obtained at least 2 replicates: adipose, adrenal gland, aorta, bone, bone-marrow, breast, buccal cells, cartilage, cerebellum, colon, diaphragm, esophagus , frontal cortex, kidney, heart, hippocampus, liver, lung, lymph node, midbrain, muscle, occipital cortex, pancreas, pericardium skin, spleen, stomach, temporal cortex, thyroid, whole blood.
 
Contributor(s) Horvath S, Coles LS
Citation(s) 26000617
Submission date Dec 23, 2014
Last update date Mar 22, 2019
Contact name Steve Horvath
E-mail(s) shorvath@altoslabs.com
Organization name University of California, Los Angeles
Department Human Genetics
Lab Horvath
Street address 695 Charles E. Young Drive South, Box 708822
City Los Angeles
State/province CA
ZIP/Postal code 90095-7088
Country USA
 
Platforms (1)
GPL13534 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482)
Samples (64)
GSM1572382 genomic DNA from Diaphragm of a 112 year old female subject (Sample1)
GSM1572383 genomic DNA from Kidney of a 112 year old female subject (Sample2)
GSM1572384 genomic DNA from BrainOccipital of a 112 year old female subject (Sample3)
This SubSeries is part of SuperSeries:
GSE64511 DNA methylation profiles of multiple human tissues
Relations
BioProject PRJNA271161

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE64491_Explanation_of_characteristic_variables2_tissue.txt.gz 691 b (ftp)(http) TXT
GSE64491_RAW.tar 183.1 Mb (http)(custom) TAR
GSE64491_datSignal_tissue.csv.gz 155.8 Mb (ftp)(http) CSV
Processed data included within Sample table

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