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| Status |
Public on Aug 24, 2015 |
| Title |
Expression data from Brakeless mutant Drosophila embryos |
| Organism |
Drosophila melanogaster |
| Experiment type |
Expression profiling by array
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| Summary |
The Brakeless protein performs many important functions during Drosophila development, but how it controls gene expression is not understood. We previously showed that Brakeless can function as a transcriptional co-repressor. Here, we report transcriptional profiling of brakeless mutant embryos to identify additional target genes.
We used microarrays to identify gene expression changes in brakeless mutant early Drosophila embryos.
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| Overall design |
Drosophila germline clones of the strong brakeless 278 allele (lab stock B97) were generated and compared to control germline clones generated with the original unmutagenized chromosome (FRT G13). Two-four hour old embryos from these females were used for RNA extraction and hybridization on Affymetrix microarrays.
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| Contributor(s) |
Crona F, Singla B, Mannervik M |
| Citation(s) |
26260775, 26509186 |
| Submission date |
Aug 04, 2014 |
| Last update date |
May 04, 2018 |
| Contact name |
Mattias Mannervik |
| E-mail(s) |
mattias.mannervik@su.se
|
| Organization name |
Stockholm University
|
| Department |
Molecular Biosciences, the Wenner-Gren Institute
|
| Lab |
Mattias Mannervik
|
| Street address |
Arrheniuslaboratories E3
|
| City |
Stockholm |
| ZIP/Postal code |
10691 |
| Country |
Sweden |
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| Platforms (1) |
| GPL1322 |
[Drosophila_2] Affymetrix Drosophila Genome 2.0 Array |
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| Samples (6)
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| GSM1464238 |
brakeless mutant embryo, biological rep1 |
| GSM1464239 |
brakeless mutant embryo, biological rep2 |
| GSM1464240 |
brakeless mutant embryo, biological rep3 |
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| Relations |
| BioProject |
PRJNA257384 |
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