|
| Status |
Public on Oct 29, 2014 |
| Title |
Synovial biopsies from RA and PsA patients and skin biopsies from Psoriasis patients under Infliximab treatment |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Object: to understand Infliximab treatment effect on the molecular expression of tissue at disease site
|
| |
|
| Overall design |
4mm punch biopsies were performed on involved and uninvolved skin at baseline in 5 Ps patients. A repeat biopsy was performed at week 2 after IFX therapy at a site adjacent to the baseline biopsy of involved skin. Synovial biopsies were performed on the knee of 3 RA and 3 PsA paired-subjects with a Parker Pearson biopsy needle (Dyna Medical, London, Canada) under ultrasound guidance at baseline and repeated on the same knee at week 10
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| |
|
| Contributor(s) |
Shealy D, Ritchlin C |
| Citation(s) |
25333715 |
| Submission date |
May 07, 2014 |
| Last update date |
Apr 20, 2018 |
| Contact name |
Christopher Ritchlin |
| E-mail(s) |
Christopher_Ritchlin@URMC.Rochester.edu
|
| Phone |
(585) 486-0901
|
| Organization name |
University of Rochester Medical Center
|
| Department |
School of Medicine and Dentistry
|
| Street address |
601 Elmwood Ave, BOX695
|
| City |
Rochester |
| State/province |
NY |
| ZIP/Postal code |
14642 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL13158 |
[HT_HG-U133_Plus_PM] Affymetrix HT HG-U133+ PM Array Plate |
|
| Samples (32)
|
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| This SubSeries is part of SuperSeries: |
| GSE57386 |
Gene expression of biopsies, CD14+ and CD14- cells from RA, PsA and PsO patients with Infliximab treatment |
|
| Relations |
| BioProject |
PRJNA246406 |
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