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Series GSE53841 Query DataSets for GSE53841
Status Public on Jun 09, 2015
Title Whole blood DNA methylation samples from HIV positive men [2012 study]
Organism Homo sapiens
Experiment type Methylation profiling by genome tiling array
Summary Genome wide DNA methylation profiles of whole blood from HIV positive men. The Illumina Infinium 450k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 480,000 CpGs. Dataset included 24 subjects from the USA. This data set was used as validation set for studying the effect of HIV viral load on host DNA methylation levels.
 
Overall design Bisulphite converted DNA from the 24 samples were hybridised to the Illumina Infinium 450k Human Methylation Beadchip. Subjects had different levels of HIV viral load.

This dataset reports DNA methylation data set on 24 subjects that were generated in 2012 (while the other data set of 120 subjects reports DNA meth data generated in 2013).

Details on what each sample characteristics and their values represent are provided in the 'characteristics_readme.txt' file.
 
Contributor(s) Horvath S, Levine AJ
Citation(s) 25969563
Submission date Jan 06, 2014
Last update date Mar 22, 2019
Contact name Steve Horvath
E-mail(s) shorvath@altoslabs.com
Organization name University of California, Los Angeles
Department Human Genetics
Lab Horvath
Street address 695 Charles E. Young Drive South, Box 708822
City Los Angeles
State/province CA
ZIP/Postal code 90095-7088
Country USA
 
Platforms (1)
GPL13534 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482)
Samples (24)
GSM1301991 genomic DNA from whole blood of HIV+ man 1 [2012]
GSM1301992 genomic DNA from whole blood of HIV+ man 2 [2012]
GSM1301993 genomic DNA from whole blood of HIV+ man 3 [2012]
Relations
BioProject PRJNA233507

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE53841_RAW.tar 183.1 Mb (http)(custom) TAR
GSE53841_characteristics_readme.txt 1.6 Kb (ftp)(http) TXT
GSE53841_non_normalized.txt.gz 59.1 Mb (ftp)(http) TXT
Processed data included within Sample table
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