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| Status |
Public on Oct 25, 2013 |
| Title |
miRNA expression data from post-partum dairy cattle (Holstein Friesian) liver |
| Platform organism |
synthetic construct |
| Sample organism |
Bos taurus |
| Experiment type |
Non-coding RNA profiling by array
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| Summary |
High yielding dairy cattle undergo a state of NEB (negative energy balance) during the post-partum period when energy demand for lactation and maintenance exceeds energy intake. During this period in order to counteract NEB the liver under goes extensive metabolic and physiological change resulting in alteration in hepatic genes and miRNAs expression.
We used Affymetrix Multispecies miRNA-2_0 Array with miRBase version 15 coverage to assess the liver miRNA expression in SNEB (severe NEB) and MNEB (mild NEB) Holstein Friesian cattle during the post-partum period.
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| Overall design |
A NEB model of Holstein Friesian was established such that 12 post-partum cattle were randomly assigned to MNEB and SNEB groups depending on different feeding and milking regimes
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| Contributor(s) |
Fatima A, Waters S, O'Boyle P, Seoighe C, Morris D |
| Citation(s) |
24428929 |
| Submission date |
Oct 24, 2013 |
| Last update date |
May 02, 2017 |
| Contact name |
Dermot G Morris |
| E-mail(s) |
dermot.morris@teagasc.ie
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| Organization name |
Teagasc
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| Department |
Animal Bioscience Research Department
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| Street address |
Animal & Grassland Research and Innovation Centre, Mellows Campus
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| City |
Athenry |
| State/province |
Co. Galway |
| ZIP/Postal code |
001 |
| Country |
Ireland |
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| Platforms (1) |
| GPL14613 |
[miRNA-2] Affymetrix Multispecies miRNA-2 Array |
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| Samples (9)
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| GSM1250216 |
HF liver MNEB, biological rep2, animal L1098 |
| GSM1250217 |
HF liver MNEB, biological rep3, animal L1106 |
| GSM1250218 |
HF liver MNEB, biological rep4, animal L330 |
| GSM1250219 |
HF liver MNEB, biological rep5, animal L245 |
| GSM1250220 |
HF liver SNEB, biological rep1, animal L3156 |
| GSM1250221 |
HF liver SNEB, biological rep3, animal L231R |
| GSM1250222 |
HF liver SNEB, biological rep4, animal L51 |
| GSM1250223 |
HF liver SNEB, biological rep5, animal L214 |
| GSM1250224 |
HF liver SNEB, biological rep6, animal L11 |
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| Relations |
| BioProject |
PRJNA224254 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE51658_RAW.tar |
5.6 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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