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| Status |
Public on Jun 23, 2006 |
| Title |
Genomic responses to Phenobarbital in Drosophila melanogaster |
| Organism |
Drosophila melanogaster |
| Experiment type |
Expression profiling by array
|
| Summary |
Phenobarbital is a well studied xenobiotic compound. In this study, we describe the genomic responses in fruit flies and examine whether animals mutant for DHR96, an ortholog of xenobiotic nuclear receptors PXR and CAR, plays a role in mediating xenobiotic responses in Drosophila.
Keywords: dose response in mutant vs. wild type
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| Overall design |
Canton S is a commonly used wild type control strain for xenobiotic studies. Wild type or DHR96 mutant flies were starved overnight and then exposed to either sucrose alone or sucrose supplemented with 0.3% Phenobarbital.
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| |
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| Contributor(s) |
King-Jones K, Horner MA, Lam G, Thummel CS |
| Citation(s) |
16814731 |
| Submission date |
Jun 16, 2006 |
| Last update date |
May 04, 2018 |
| Contact name |
Kirst King-Jones |
| E-mail(s) |
kingjone@ualberta.ca
|
| Phone |
780-4928605
|
| Organization name |
University of Alberta
|
| Department |
Biological Sciences
|
| Lab |
King-Jones
|
| Street address |
77 University Campus
|
| City |
Edmonton |
| State/province |
AB |
| ZIP/Postal code |
T6H 5V3 |
| Country |
Canada |
| |
|
| Platforms (1) |
| GPL1322 |
[Drosophila_2] Affymetrix Drosophila Genome 2.0 Array |
|
| Samples (12)
|
| GSM114985 |
Genomic responses to Phenobarbital CSSUC1 |
| GSM114986 |
Genomic responses to Phenobarbital CSSUC2 |
| GSM114987 |
Genomic responses to Phenobarbital CSSUC3 |
| GSM114988 |
Genomic responses to Phenobarbital E25SUC1 |
| GSM114989 |
Genomic responses to Phenobarbital E25SUC2 |
| GSM114990 |
Genomic responses to Phenobarbital E25SUC3 |
| GSM114991 |
Genomic responses to Phenobarbital CSPB1 |
| GSM114992 |
Genomic responses to Phenobarbital CSPB2 |
| GSM114993 |
Genomic responses to Phenobarbital CSPB3 |
| GSM114994 |
Genomic responses to Phenobarbital E25PB1 |
| GSM114995 |
Genomic responses to Phenobarbital E25PB2 |
| GSM114996 |
Genomic responses to Phenobarbital E25PB3 |
|
| Relations |
| BioProject |
PRJNA95347 |
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