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| Status |
Public on Jan 01, 2015 |
| Title |
Mucosal miRNA expression profiling in (un)inflamed colon of patients with ulcerative colitis (UC) |
| Platform organism |
synthetic construct |
| Sample organism |
Homo sapiens |
| Experiment type |
Non-coding RNA profiling by array
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| Summary |
In this study, we investigated if miRNA expression in UC mucosa is altered and correlated our findings with mucosal mRNA expression. Integration of mRNA and miRNA expression profiling may allow the identification of functional links between dysregulated miRNAs and their predicted target mRNA.
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| Overall design |
Colonic mucosal biopsies were obtained during endoscopy from 17 UC (10 active and 7 inactive) patients and 10 normal controls. Total RNA, including small RNA, was isolated from colonic mucosal biopsies, labelled and hybridized to Affymetrix Genechip miRNA 2.0 Arrays.
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| Contributor(s) |
Van der Goten J, Van Lommel L, Ferrante M, Van Assche G, Rutgeerts P, Schuit F, Vermeire S, Arijs I |
| Citation(s) |
25546151 |
| Submission date |
Jul 17, 2013 |
| Last update date |
May 02, 2017 |
| Contact name |
Jan Van der Goten |
| E-mail(s) |
jan.vandergoten@med.kuleuven.be
|
| Organization name |
KU Leuven
|
| Department |
Clinical and Experimental Medicine
|
| Lab |
TARGID - IBD Leuven
|
| Street address |
Herestraat 49 bus 701
|
| City |
Leuven |
| ZIP/Postal code |
3000 |
| Country |
Belgium |
| |
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| Platforms (1) |
| GPL14613 |
[miRNA-2] Affymetrix Multispecies miRNA-2 Array |
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| Samples (27)
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| This SubSeries is part of SuperSeries: |
| GSE48959 |
Mucosal expression profiling in (un)inflamed colon of patients with ulcerative colitis (UC) |
|
| Relations |
| BioProject |
PRJNA212401 |
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