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| Status |
Public on Apr 28, 2006 |
| Title |
Effect of a high fat diet on the hypothalami of mice susceptible to diet-induced obesity KOZAK2_ABI_HYP |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
The experimental goals of this study were to determine the differences in hypothalamus gene expression in genetically identical mice that have variability in their susceptibility towards diet-induced obesity following 6 weeks feeding a high fat diet, 2 weeks low fat diet and 6 weeks high fat diet.
Keywords: Comparative gene expression analysis
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| Overall design |
Gene expression analyses was performed from pooled hypothalamus RNA from male C57BL/6J mice exhibiting high or low weight gain after 6 weeks feeding a high fat diet, 2 weeks low fat diet and 6 weeks high fat diet. Four technical replicates were performed for each pool of RNA from high (H1, H2, H3, and H4) and low (L1, L2, L3, and L4) weight gaining mice.
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| Contributor(s) |
Koza RA, Nikonova L, Hogan JC, Rim JS, Mendoza T, Faulk C, Skaf J, Kozak LP |
| Citation(s) |
16733553 |
| Submission date |
Apr 21, 2006 |
| Last update date |
Mar 16, 2012 |
| Contact name |
Jessica C Hogan |
| E-mail(s) |
hoganjc@pbrc.edu
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| Phone |
225-763-3143
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| Fax |
225-763-0273
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| Organization name |
Pennington Biomedical Research Center
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| Department |
Molecular Genetics
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| Street address |
6400 Perkins Rd.
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| City |
Baton Rouge |
| State/province |
LA |
| ZIP/Postal code |
70808 |
| Country |
USA |
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| Platforms (1) |
| GPL2995 |
ABI Mouse Genome Survey Microarray |
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| Samples (8)
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| GSM106159 |
High weight gainer KOZAK2_ABI_HYP_H1 |
| GSM106160 |
High weight gainer KOZAK2_ABI_HYP_H2 |
| GSM106161 |
High weight gainer KOZAK2_ABI_HYP_H3 |
| GSM106162 |
High weight gainer KOZAK2_ABI_HYP_H4 |
| GSM106163 |
Low weight gainer KOZAK2_ABI_HYP_L1 |
| GSM106164 |
Low weight gainer KOZAK2_ABI_HYP_L2 |
| GSM106165 |
Low weight gainer KOZAK2_ABI_HYP_L3 |
| GSM106166 |
Low weight gainer KOZAK2_ABI_HYP_L4 |
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| Relations |
| BioProject |
PRJNA96747 |
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