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| Status |
Public on Jan 01, 2007 |
| Title |
Transcriptomics in cardiac surgery |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Anesthetic gases elicit organ protection in patients undergoing coronary artery bypass graft (CABG) surgery. This study aimed at identifying myocardial transcriptional phenotypes and anesthetic-induced changes in gene expression to predict cardiovascular biomarkers and cardiac function after off-pump CABG.
Keywords: cardiac surgery, anesthetics
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| |
|
| Overall design |
Patients scheduled for off-pump CABG were randomized into a group with the anesthetic gas sevoflurane (n=10) or the intravenous anesthetic propofol (n=10). Atrial samples were collected at the beginning and end of bypass surgery to determine gene expression profiles.
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| |
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| Contributor(s) |
Lucchinetti E, Zaugg M |
| Citation(s) |
17325502 |
| Submission date |
Mar 07, 2006 |
| Last update date |
Mar 25, 2019 |
| Contact name |
Michael Zaugg |
| E-mail(s) |
michael.zaugg@usz.ch
|
| Phone |
+41-1-255 11 11
|
| Organization name |
Anesthesiology, University Hospital Zurich
|
| Department |
Anesthesiology
|
| Lab |
Perioperative Cardioprotection Research Group
|
| Street address |
Raemistrasse 100
|
| City |
Zurich |
| ZIP/Postal code |
8091 |
| Country |
Switzerland |
| |
|
| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
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| Samples (40)
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| Relations |
| BioProject |
PRJNA94569 |
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