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| Status |
Public on Dec 10, 2005 |
| Title |
Comparison of gene expression profiles of p63 null skin versus wild type skin |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
In the absence of p63 expression, the epidermis fails to commit to stratification, resulting in aborted skin development. In this study, gene expression profiles of E18.5 p63 null and wt skin, were compared in an effort to identify genes that are directly or indirectly regulated by p63.
Keywords: Genetically modified mice
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| Overall design |
E18.5 embryos were obtained from matings between p63 heterozygous mice. RNA was isolated from the skin of two p63 null and two wild type embryos.
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| Contributor(s) |
Kim S, Roop DR |
| Citation(s) |
16324689 |
| Submission date |
Aug 10, 2005 |
| Last update date |
Feb 18, 2018 |
| Contact name |
Maranke Koster |
| E-mail(s) |
mkoster@bcm.tmc.edu
|
| Organization name |
Baylor College of Medicine
|
| Department |
Molecular and Cellular Biology
|
| Street address |
One Baylor Plaza, Room T707
|
| City |
Houston |
| State/province |
TX |
| ZIP/Postal code |
77030 |
| Country |
USA |
| |
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| Platforms (2) |
| GPL81 |
[MG_U74Av2] Affymetrix Murine Genome U74A Version 2 Array |
| GPL82 |
[MG_U74Bv2] Affymetrix Murine Genome U74B Version 2 Array |
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| Samples (8)
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| Relations |
| BioProject |
PRJNA93115 |
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