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| Status |
Public on Feb 01, 2011 |
| Title |
Expression data from Drosophila dLmo (EP1306 and BxJ) mutants |
| Organism |
Drosophila melanogaster |
| Experiment type |
Expression profiling by array
|
| Summary |
The Drosophila gene dLmo encodes a transcriptional regulator involved in wing development and behavioral responses to cocaine and ethanol.
We were interested in discovering novel transcriptional targets of dLmo in the nervous system by examining gene expression changes in the heads of wild-type flies and flies carrying dLmo loss-of-function (EP1306) and gain-of-function mutants (BxJ).
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| Overall design |
RNA was isolated from 3 pooled groups of 200 fly heads from each genotype (w;iso control, EP1306, and BxJ) and hybridized to triplicate Affymetrix Drosophila 2.0 oligonucleotide microarray chips at the Partners HealthCare Center for Personalized Genetic Medicine microarray facility (Harvard University).
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| Contributor(s) |
Lasek AW, Heberlein U, Moore MS |
| Citation(s) |
21799923 |
| Submission date |
Dec 10, 2010 |
| Last update date |
Aug 28, 2018 |
| Contact name |
Amy Lasek |
| E-mail(s) |
alasek@gallo.ucsf.edu
|
| Organization name |
Ernest Gallo Clinic and Research Center/UCSF
|
| Department |
Neurology
|
| Lab |
Heberlein
|
| Street address |
5858 Horton Street, Suite 200
|
| City |
Emeryville |
| State/province |
CA |
| ZIP/Postal code |
94608 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL1322 |
[Drosophila_2] Affymetrix Drosophila Genome 2.0 Array |
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| Samples (9)
|
| GSM637975 |
adult head RNA from BxJ mutant, replicate 1 |
| GSM637976 |
adult head RNA from BxJ mutant, replicate 2 |
| GSM637977 |
adult head RNA from BxJ mutant, replicate 3 |
| GSM637978 |
adult head RNA from EP1306 mutant, replicate 1 |
| GSM637979 |
adult head RNA from EP1306 mutant, replicate 2 |
| GSM637980 |
adult head RNA from EP1306 mutant, replicate 3 |
| GSM637981 |
adult head RNA from w;iso control flies, replicate 1 |
| GSM637982 |
adult head RNA from w;iso control flies, replicate 2 |
| GSM637983 |
adult head RNA from w;iso control flies, replicate 3 |
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| Relations |
| BioProject |
PRJNA135415 |
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