|
| Status |
Public on Aug 09, 2023 |
| Title |
Illumina 450k methylation data from colon polyps |
| Organism |
Homo sapiens |
| Experiment type |
Methylation profiling by genome tiling array
|
| Summary |
The tubular adenoma sample cohort (accrued by Janssen Pharmaceuticals) consisted of 127 high-risk baseline adenoma samples acquired retrospectively by Avaden Biosciences. High risk patients are defined here as presenting a tubular adenoma ? 10mm, 3 or more adenomas, adenomas with villous histology or adenomas showing high-grade dysplasia based on Lieberman et al.
Patients with familial adenomatous polyposis (FAP) and Lynch syndrome were excluded. All patients received at least one baseline colonoscopy for which clinical and pathological records were available. Adenoma tissue was available as archival, formalin-fixed, paraffin-embedded (FFPE) blocks.
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| |
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| Overall design |
Illumina Infinium 450K beadchip dataset from 61 colon polyp samples
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| |
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| Contributor(s) |
Bhandari YR, Krishna V, Powers R, Parmar S, Thursby S, Gupta E, Kulak O, Gokare P, Reumers J, Van Wesenbeeck L, Bachman KE, Baylin SB, Easwaran H |
| Citation(s) |
37487069 |
| Submission date |
May 26, 2023 |
| Last update date |
Aug 10, 2023 |
| Contact name |
Yuba R Bhandari |
| E-mail(s) |
ybhanda2@jhmi.edu
|
| Organization name |
The Johns Hopkins University School of Medicine
|
| Street address |
1650 Orleans Street
|
| City |
Baltimore |
| State/province |
MD |
| ZIP/Postal code |
21287 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL13534 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482) |
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| Samples (61)
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| This SubSeries is part of SuperSeries: |
| GSE233616 |
Transcription factor expression repertoire basis for epigenetic and transcriptional subtypes of colorectal cancers |
|
| Relations |
| BioProject |
PRJNA976734 |
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