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Series GSE20716 Query DataSets for GSE20716
Status Public on Jun 30, 2014
Title PBMC expression profiles of BCG vaccine protected infants and of BCG vaccinated infants who develop tuberculosis disease
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Analysis of PBMC from 10 week old infants vaccinated with BCG at birth. During follow-up 26 infants developed tuberculosis (TB) (non-protected by BCG) and 20 infants did not develop TB despite documented exposure (protected by BCG). PBMC were stimulated with media only or reconstituted BCG for 4 and 12 hours. Results provide insight into the mechanisms behind the failure of BCG to protect against disease.
 
Overall design Set of arrays that are part of repeated experiments
 
Contributor(s) Fletcher HA, Hanekom W
Citation(s) 27183822
Submission date Mar 09, 2010
Last update date Jan 27, 2017
Contact name Helen Alison Fletcher
E-mail(s) helen.fletcher@lshtm.ac.uk
Phone +44 (0) 20 7927 2666
Organization name London School of Hygiene & Tropical Medicine
Department IID
Street address Keppel Street
City London
ZIP/Postal code W1CE 7HT
Country United Kingdom
 
Platforms (1)
GPL6255 Illumina humanRef-8 v2.0 expression beadchip
Samples (182)
GSM520000 12406_case_4hrs_unstimulated
GSM520001 18195_case_4hrs_unstimulated
GSM520002 14116_case_4hrs_BCG_stimulated
Relations
BioProject PRJNA124911

Download family Format
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Supplementary data files not provided
Processed data included within Sample table
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