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| Status |
Public on Jan 14, 2010 |
| Title |
Expression data from murine hearts exposed to ischemic preconditioning comparing A2BAR null and wildtype BL6/C57 mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Genetically targeted mice with deficiency for the A2BAR show increased susceptibility to acute myocardial ischemia and are not protected by IP, a powerful strategy for cardioprotection, where short and repeated episodes of ischemia and reperfusion prior to myocardial infarction result in attenuation of infarct size.
The purpose of this study was to identify genes that are potentially under the control of the cardiac A2B adenosine receptor
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| Overall design |
Untreated wildtype and A2BAR-/- mice were compared to wildtype and A2BAR-/- mice with IP treatment following a 2 hours reperfusion period
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| Contributor(s) |
Eckle T, Walter M |
| Citation(s) |
22504483 |
| Submission date |
Jan 13, 2010 |
| Last update date |
Feb 11, 2019 |
| Contact name |
Tobias Eckle |
| E-mail(s) |
tobias.eckle@ucdenver.edu
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| Phone |
72-949-5646
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| Organization name |
UC Denver
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| Department |
Anesthesiology
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| Street address |
12700 E 19th Avenue
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| City |
Denver |
| State/province |
CO |
| ZIP/Postal code |
80045 |
| Country |
USA |
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| Platforms (1) |
| GPL1261 |
[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array |
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| Samples (12)
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| GSM496718 |
A2BAR -/- mouse heart, control, rep1 |
| GSM496719 |
A2BAR -/- mouse heart, control, rep2 |
| GSM496720 |
A2BAR -/- mouse heart, control, rep3 |
| GSM496721 |
BL6/C57 mouse heart IP120, rep1 |
| GSM496722 |
BL6/C57 mouse heart IP120, rep2 |
| GSM496723 |
BL6/C57 mouse heart IP120, rep3 |
| GSM496724 |
BL6/C57 mouse heart, control, rep1 |
| GSM496725 |
BL6/C57 mouse heart, control, rep2 |
| GSM496726 |
BL6/C57 mouse heart, control, rep3 |
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| Relations |
| BioProject |
PRJNA121971 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE19875_I7R_043_genelists.xls.gz |
10.9 Mb |
(ftp)(http) |
XLS |
| GSE19875_RAW.tar |
47.3 Mb |
(http)(custom) |
TAR (of CEL, CHP) |
| Processed data included within Sample table |
| Processed data provided as supplementary file |
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