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| Status |
Public on Jan 21, 2024 |
| Title |
Effect of the Foxp3 inhibitory peptide P60 on gene array expression of Karpas cell line |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
By using a phage displayed peptide library we identified peptide P60 as able to bind Foxp3 and inhibit Treg activity. To gain insight into the effect of P60 in Foxp3+ve cells we used Karpas 299 human cell line derived from a human lymphoma with a regulatory T cell profile. Microarray analysis of Karpas cell line incubated with or without P60 peptide was carried out using the Affymetrix human U133 Plus 2.0 array.
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| Overall design |
Two culture condition (absence or presence of P60 peptide in the culture) were studied in two replicates
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| Contributor(s) |
Lasarte JJ |
| Citation missing |
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| Submission date |
Jan 21, 2021 |
| Last update date |
Jan 22, 2024 |
| Contact name |
Juan Jose Lasarte |
| E-mail(s) |
jjlasarte@unav.es
|
| Phone |
+34 948 194700
|
| Organization name |
Centro de Investigación Médica Aplicada
|
| Department |
Inmunología e Inmunoterapia
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| Lab |
3.02
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| Street address |
Avda Pio XII, 55
|
| City |
Pamplona |
| State/province |
Navarra |
| ZIP/Postal code |
31008 |
| Country |
Spain |
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| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA693835 |
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