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| Status |
Public on Aug 09, 2022 |
| Title |
RNA-seq Analysis of sibling and dhx38-- zebrafish |
| Organism |
Danio rerio |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Purpose: Loss of dhx38 disrupts the proliferation and differentiation balance of hematopoiesis. Notably, the mitosis of both EMPs and HSPCs are blocked in the pre-metaphase with abnormal chromatin karyotype in the dhx38--zebrafish. RNA-seq analysis screened abnormal splicing and aberrant expression genes that are likely to explain the dysfunction of mitosis.
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| |
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| Overall design |
Tail tissue mRNA profiles of 36 hpf sibling (WT) and dhx38--zebrafish
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| |
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| Contributor(s) |
Tu J, Li J, Luo J |
| Citation missing |
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| Submission date |
Jan 20, 2021 |
| Last update date |
Aug 09, 2022 |
| Contact name |
Jiayi Tu |
| E-mail(s) |
jiayitu@hust.edu.cn
|
| Phone |
13297921528
|
| Organization name |
Huazhong university of science and technology
|
| Street address |
LUOYU ROAD
|
| City |
WuHan |
| ZIP/Postal code |
430000 |
| Country |
China |
| |
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| Platforms (1) |
| GPL14875 |
Illumina HiSeq 2000 (Danio rerio) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA693543 |
| SRA |
SRP302579 |
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