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| Status |
Public on Jun 20, 2023 |
| Title |
Impact of PRRX1 knockdown on the transcriptome of normal human lung fibroblasts (NHLF) in the presence or the absence of TGF-β |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
To assess the role of PRRX1 in TGF-β-induced lung fibroblast activation, we transfected in human NHLF with PRRX1 or control siRNAs and then exposed these cells to TGF- β (1 ng/mL). RNA samples were harvested 48 hours after TGF-β exposition. Two independent experiments were carried out.
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| Overall design |
2 independent experiments performed in a one color design, corresponding to 8 conditions (siControl#1, siControl#1+TGF-β, siControl#2, siControl#2+TGF-β, PRRX1siRNA#1, PRRX1siRNA#1 +TGF-β, PRRX1 siRNA#2, PRRX1siRNA#2 +TGF-β) for a total of 16 samples.
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| Web link |
https://www.genomique.info:8080/merge/index
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| Contributor(s) |
N. M, B. M, K. L, Carine M |
| Citation(s) |
37261432 |
| Submission date |
Nov 12, 2020 |
| Last update date |
Jun 21, 2023 |
| Contact name |
Kevin Lebrigand |
| Organization name |
IPMC/CNRS
|
| Lab |
Functional Genomics Platform of Nice-Sophia-Antipolis, France.
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| Street address |
660 route des lucioles
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| City |
Valbonne - Sophia-Antipolis |
| ZIP/Postal code |
06560 |
| Country |
France |
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| Platforms (1) |
| GPL21185 |
Agilent-072363 SurePrint G3 Human GE v3 8x60K Microarray 039494 [Probe Name Version] |
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| Samples (16)
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| Relations |
| BioProject |
PRJNA677966 |
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