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| Status |
Public on Apr 01, 2009 |
| Title |
Transcriptional response of Drosophila cells to FHV RNA1 replicon expression (replicon experiment) |
| Organism |
Drosophila melanogaster |
| Experiment type |
Expression profiling by array
|
| Summary |
Virus infections induce cellular gene up and down regulation, and these changes often provide clues to cellular pathways utilized by viruses.
We used microarrays to examine the transcriptional responses of cultured Drosophila S2 cells to Flock House virus (FHV) replicon induction.
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| Overall design |
Cultured S2 cells stably transfected with either a control replicon (pS2F1fs) or an FHV RNA1 replicon (pS2F1) were induced with 1 mM copper and we measured global transcript levels at 18 h after induction using Affymetrix Drosophila Genome 2.0 microarray chips.
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| |
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| Contributor(s) |
Miller DJ |
| Citation(s) |
20236518 |
| Submission date |
Mar 31, 2009 |
| Last update date |
Aug 28, 2018 |
| Contact name |
David Miller |
| E-mail(s) |
milldavi@umich.edu
|
| Phone |
734-763-0565
|
| Organization name |
University of Michigan
|
| Department |
Internal Medicine
|
| Street address |
3560B MSRB II, 1150 W. Medical Center Dr.
|
| City |
Ann Arbor |
| State/province |
MI |
| ZIP/Postal code |
48109-5688 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL1322 |
[Drosophila_2] Affymetrix Drosophila Genome 2.0 Array |
|
| Samples (4)
|
| GSM388047 |
control replicon expressing S2 cells |
| GSM388048 |
FHV RNA1 replicon expressing S2 cells, biological replicate 1 |
| GSM388049 |
FHV RNA1 replicon expressing S2 cells, biological replicate 2 |
| GSM388050 |
FHV RNA1 replicon expressing S2 cells, biological replicate 3 |
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| This SubSeries is part of SuperSeries: |
| GSE15469 |
Transcriptional response of Drosophila cells to FHV RNA replication |
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| Relations |
| BioProject |
PRJNA122969 |
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