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| Status |
Public on Sep 09, 2021 |
| Title |
Gene expression signatures of A2058 cells treated with neopetasin, metformin, and phenformin |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
To examine the difference of gene expression profiles between malignant melanoma cells treated with neopetasin (NP), metformin (Met), and phenformin (Phen), we have employed microarray expression profiling as a discovery platform. A2058 (human malignant melanoma) cells were treated for 8 hours with NP (3 µM), Met (5,00 µM), and Phen (50 µM).
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| Overall design |
Gene expression in a human malignant melanoma cell line (A2058) treated with NP, Met, and Phen was measured at 8 hours after exposure to doses of 3, 5000, 50 µM of NP, Met, and Phen, respectively. Due to different solvent employed for each compound, profiles of the cells treated with NP was compared to that of DMSO; and, the profiles of the cells treated with Met and Phen were compared to that of water. Three independent experiments were performed.
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| Contributor(s) |
Heishima K |
| Citation(s) |
34623325 |
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https://0-dx-doi-org.brum.beds.ac.uk/10.1172%2FJCI139933
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| Submission date |
May 11, 2020 |
| Last update date |
Nov 18, 2021 |
| Contact name |
Kazuki Heishima |
| Organization name |
Gifu University
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| Street address |
Yanagido 1-1
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| City |
Gifu |
| ZIP/Postal code |
5011194 |
| Country |
Japan |
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| Platforms (1) |
| GPL21185 |
Agilent-072363 SurePrint G3 Human GE v3 8x60K Microarray 039494 [Probe Name Version] |
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| Samples (15)
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| Relations |
| BioProject |
PRJNA631798 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE150348_RAW.tar |
46.0 Mb |
(http)(custom) |
TAR (of TXT) |
| Processed data included within Sample table |
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