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| Status |
Public on Dec 09, 2020 |
| Title |
High-throughput sequencing of zebrafish wild-type and duox mutant larvae |
| Organism |
Danio rerio |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
To determine the molecular basis for the dual oxidase in circulation in duox mutant zebrafish, we performed high-throughput sequencing at 4 dpf. Results revealed 375 up-regulated genes and 360 down-regulated genes in the duox mutant zebrafish compared with wild-type zebrafish. We found that some mitochondrial genes are down-regulated in duox mutant zebrafish, which was reconfirmed with qRT-PCR.
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| |
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| Overall design |
mRNA profiles of 4 dpf wild-type and duox mutant zebrafish were generated by deep seqeuncing.
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| |
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| Contributor(s) |
Dalong R, Leiqing Y |
| Citation(s) |
33123984 |
| Submission date |
Feb 03, 2020 |
| Last update date |
Dec 09, 2020 |
| Contact name |
bing hu |
| Organization name |
University of Science and Technology of China
|
| Street address |
School of Life Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230026, China
|
| City |
Hefei |
| ZIP/Postal code |
230026 |
| Country |
China |
| |
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| Platforms (1) |
| GPL14875 |
Illumina HiSeq 2000 (Danio rerio) |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA604591 |
| SRA |
SRP246913 |
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