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Status |
Public on May 07, 2020 |
Title |
Nanog affects establishment of chromatin marks at zebrafish Zygotic Genome Activation |
Organism |
Danio rerio |
Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
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Summary |
In zebrafish embryos, the maternal transcription factors (TFs)Nanog, Pou5f3 and Sox19b activate the early zygotic gene expression. To evaluate the role of Nanog, we examined the changes in H3K27ac and H3K4me3 chromatin modifications in the MZnanog embryos mutant by maternal and zygotic Nanog.
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Overall design |
We performed ChIP-seq for H3K27ac and H3K4me3 chromatin modifications in the embryos mutant by Nanog transcription factor (MZnanog). Experiments were performed at dome stage (4.3 hours post-fertilization (hpf).
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Contributor(s) |
Gebhard A, Onichtchouk D |
Citation(s) |
37709752 |
Submission date |
Jan 10, 2020 |
Last update date |
Sep 21, 2023 |
Contact name |
Daria Onichtchouk |
E-mail(s) |
daria.onichtchouk@biologie.uni-freiburg.de
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Phone |
00497612032595
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Organization name |
University of Freiburg
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Street address |
Hauptstrasse 1
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City |
Freiburg |
ZIP/Postal code |
79104 |
Country |
Germany |
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Platforms (1) |
GPL14875 |
Illumina HiSeq 2000 (Danio rerio) |
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Samples (4)
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Relations |
BioProject |
PRJNA600508 |
SRA |
SRP241206 |