|
| Status |
Public on Dec 01, 2019 |
| Title |
Insights from long non-coding RNAs profiling of beta cells undergoing high glucose/palmitate -induced glucolipotoxicity |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
RNA-Seq was performed to compare the control INS-1 cells (rat beta cell line)with the high glucose/palmitate-treated INS-1 cells. According to the expression profiling data, 264 significantly dysregulated lncRNAs were identified with a set filter (fold-change ≥2.0, p < 0.05) in the HG/PA-treated INS-1 cells: 153 were up-regulated, while 111 were down-regulated.
|
| |
|
| Overall design |
Identify the lncRNAs that are differentially expressed in high glucose/palmitate-treated INS-1 beta cells by RNA sequencing
|
| |
|
| Contributor(s) |
Kong X, Kun LV |
| Citation(s) |
31737170 |
| Submission date |
Jan 08, 2019 |
| Last update date |
Apr 10, 2020 |
| Contact name |
Xiang Kong |
| E-mail(s) |
wnmcyaolikx@163.com
|
| Organization name |
The First Aflliated Hospital of Wannan Medical College
|
| Department |
Central Laboratory of Yijishan Hospital
|
| Street address |
zheshanxi road NO 2
|
| City |
WUhu |
| ZIP/Postal code |
241001 |
| Country |
China |
| |
|
| Platforms (1) |
| GPL18694 |
Illumina HiSeq 2500 (Rattus norvegicus) |
|
| Samples (6)
|
|
| Relations |
| BioProject |
PRJNA513886 |
| SRA |
SRP176764 |
Less...
More...