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Series GSE12452 Query DataSets for GSE12452
Status Public on Aug 16, 2008
Title mRNA expression profiling of nasopharyngeal carcinoma
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Nasopharyngeal carcinoma is an Epstein-Barr virus-associated epithelial cancer with high prevalence in Southeast Asia. mRNA expression levels were measured for essentially all human genes and all latent Epstein-Barr virus (EBV) genes in nasopharyngeal carcinoma tissue samples and normal nasopharyngeal tissues. Data were analyzed for differential gene expression between tumor and normal tissue and for correlations with levels of viral gene expression. Primary publications: Sengupta et al, 2006, Cancer Research 66(16): 7999-8006. Dodd et al, 2006, Cancer Epidemiology, Biomarkers & Prevention 15(11): 2216-2225.
In subsequent studies using the same set of tissue samples, microRNA levels were measured in tumors and normal tissues and analyzed for correlations with differential target gene expression (Sengupta et al, 2008, Proc. Nat. Acad. Sci. USA 105: 5874-5878.)

Keywords: mRNA expression profiling
 
Overall design Total RNA extracted from laser-captured epithelium from 31 nasopharyngeal carcinomas and 10 normal healthy nasopharyngeal tissue specimens.
 
Contributor(s) Ahlquist P
Citation(s) 17119049, 16912175, 22880099
Submission date Aug 14, 2008
Last update date Mar 25, 2019
Contact name Paul Ahlquist
E-mail(s) ahlquist@wisc.edu
Organization name University of Wisconsin-Madison
Department Oncology
Street address 1525 Linden Dr.
City Madison
State/province WI
ZIP/Postal code 53706
Country USA
 
Platforms (1)
GPL570 [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Samples (41)
GSM312896 normal nasopharyngeal tissue, specimen N1
GSM312897 normal nasopharyngeal tissue, specimen N2
GSM312898 normal nasopharyngeal tissue, specimen N3
Relations
BioProject PRJNA113009

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE12452_RAW.tar 205.8 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table
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