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| Status |
Public on Jul 12, 2008 |
| Title |
Gene Expression Profiling Separates Chromophobe Renal Cell Carcinoma from Oncocytoma |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
This study aims to compare gene expression profiles of chromophobe renal cell carcinoma (RCC) and benign oncocytoma, aiming at identifying differentially expressed genes.
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| |
|
| Overall design |
Nine cases each of chromophobe RCC and oncocytoma were analyzed by oligonucleotide microarray. Candidate genes that showed consistent differential expression were validated by RT-PCR using 25 fresh-frozen and 15 formalin-fixed paraffin-embedded tumor samples. Immunohistochemical analysis was also performed for two selected gene products, Claudin 8 and MAL2.
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| |
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| Contributor(s) |
Rohan S, Tu JJ, Kao J, Mukherjee P, Campagne F, Zhou XK, Hyjek E, Alonso MA, Chen Y |
| Citation(s) |
17145811 |
| Submission date |
Jul 11, 2008 |
| Last update date |
Mar 25, 2019 |
| Contact name |
Piali Mukherjee |
| E-mail(s) |
pim2001@med.cornell.edu
|
| Organization name |
Weill Cornell Medicine
|
| Department |
Medicine
|
| Lab |
Epigenomics Core
|
| Street address |
1300 York Ave. C-545
|
| City |
NEW YORK |
| State/province |
New York |
| ZIP/Postal code |
10065 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
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| Samples (18)
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| Relations |
| BioProject |
PRJNA113527 |
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