|
| Status |
Public on Feb 06, 2018 |
| Title |
RUNX2 promotes the development of Blastic plasmacytoid dendritic cell neoplasm (BPDCN) |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
To understand how RUNX2 promoted the development of BPDCN, we transduced RUNX2-directed shRNA vectors in a BPDCN cell line, CAL-1 and performed microarray analysis of RUNX2-knocked down CAL-1 cells
|
| |
|
| Overall design |
CAL-1 cells were transduced with two distinct RUNX2-directed shRNA vectors containing IRES-GFP. As RUNX2-directed shRNA-transduced cells significantly reduced levels of RUNX2 expression, compared to the control Luciferase-directed shRNA-transduced cells, we perfomed gene expression analysis of RUNX2-knocked down CAL-1 cells.
|
| |
|
| Contributor(s) |
Sashida G, Kubota S |
| Citation(s) |
30971697 |
| Submission date |
Feb 05, 2018 |
| Last update date |
Apr 23, 2019 |
| Contact name |
Goro Sashida |
| Organization name |
Kumamoto University
|
| Department |
IRCMS
|
| Lab |
Transcriptional Regulation in Leukemogenesis
|
| Street address |
2-2-1 Honjo, Chuo-ku
|
| City |
Kumamoto |
| State/province |
Kumamoto |
| ZIP/Postal code |
860-0811 |
| Country |
Japan |
| |
|
| Platforms (1) |
| GPL21185 |
Agilent-072363 SurePrint G3 Human GE v3 8x60K Microarray 039494 [Probe Name Version] |
|
| Samples (3) |
|
| Relations |
| BioProject |
PRJNA432940 |
