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Status |
Public on Oct 20, 2019 |
Title |
Impact of cognitive performance and normal aging on transcriptomic changes in the prefrontal cortex of rats |
Organism |
Rattus norvegicus |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
We investigated how cognitive stimulation impacts gene expression in the prefrontal cortex (PFC), a brain region known to regulate higher cognitive functions including the control of attention, in young and aged rats.
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Overall design |
2x2 design: 2 (cognitive performance [2 levels: performing, non performing) x 2 (age [2 levels: young, old])
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Contributor(s) |
Parikh V, Tan Y, Ross EA, Slifker M, Joshi S, Wimmer M, Duggan MR |
Citation(s) |
31185277 |
NIH grant(s) |
Grant ID |
Grant title |
Affiliation |
Name |
R21 AG046580 |
Cholinergic overload and resilience to attentional capacities in aging |
TEMPLE UNIVERSITY |
Vinay Parikh |
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Submission date |
Oct 20, 2017 |
Last update date |
Jan 20, 2020 |
Contact name |
Vinay Parikh |
E-mail(s) |
vinay.parikh@temple.edu
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Phone |
215-204-1572
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Organization name |
Temple University
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Department |
Psychology
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Street address |
1701 N. 13th Street, Weiss Hall
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City |
Philadelphia |
State/province |
PA |
ZIP/Postal code |
19122 |
Country |
USA |
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Platforms (1) |
GPL18694 |
Illumina HiSeq 2500 (Rattus norvegicus) |
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Samples (12)
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Relations |
BioProject |
PRJNA415196 |
SRA |
SRP120613 |