EPHA7 EPH receptor A7 [Gallus gallus (chicken)] - Gene

Summary

Symbol: EPHA7provided by CGNC
Full Name: EPH receptor A7provided by CGNC
Primary source: CGNC:49580
See related: Ensembl:ENSGALG00010004127
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: CEPHA7
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 19

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	3	NC_052534.1 (73598654..73758206)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	3	NC_052575.1 (73393092..73552665)

Chromosome 3 - NC_052534.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

EphA7 receptor is expressed differentially at chicken prosomeric boundaries.
Title: EphA7 receptor is expressed differentially at chicken prosomeric boundaries.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed
enables transmembrane-ephrin receptor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in axon guidance	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cell surface receptor protein tyrosine kinase signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in neuron projection	IEA Inferred from Electronic Annotation more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: ephrin type-A receptor 7

Names: EK11; EPH-like kinase 11; Eph-like receptor tyrosine kinase; cEK11; tyrosine-protein kinase receptor CEPHA7

NP_001384405.1

EC 2.7.10.1

NP_001384406.1

EC 2.7.10.1

NP_990414.1

EC 2.7.10.1

XP_040552779.1

EC 2.7.10.1

XP_040552780.1

EC 2.7.10.1

XP_040552783.1

EC 2.7.10.1

XP_040552784.1

EC 2.7.10.1

XP_046769140.1

EC 2.7.10.1

XP_046769141.1

EC 2.7.10.1

XP_046769142.1

EC 2.7.10.1

XP_046769143.1

EC 2.7.10.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001397476.1 → NP_001384405.1 ephrin type-A receptor 7 isoform 2 precursor

Status: VALIDATED

Source sequence(s)

JAENSK010000065

UniProtKB/TrEMBL

A0A8V0XLI2

Related

ENSGALP00010005648.1, ENSGALT00010009622.1

Conserved Domains (6) summary

cd09548
Location:910 → 979

SAM_EPH-A7; SAM domain of EPH-A7 subfamily of tyrosine kinase receptors

cd10485
Location:30 → 206

EphR_LBD_A7; Ligand Binding Domain of Ephrin type-A Receptor 7

cd00063
Location:443 → 534

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd05066
Location:619 → 885

PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors

pfam00041
Location:333 → 427

fn3; Fibronectin type III domain

pfam14575
Location:560 → 621

EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
NM_001397477.1 → NP_001384406.1 ephrin type-A receptor 7 isoform 3 precursor

Status: VALIDATED

Source sequence(s)

JAENSK010000065

UniProtKB/TrEMBL

A0A8V0XG19

Related

ENSGALP00010005649.1, ENSGALT00010009623.1

Conserved Domains (3) summary

cd10485
Location:30 → 206

EphR_LBD_A7; Ligand Binding Domain of Ephrin type-A Receptor 7

cd00063
Location:443 → 534

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd05066
Location:623 → 889

PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
NM_205083.2 → NP_990414.1 ephrin type-A receptor 7 isoform 1 precursor

See identical proteins and their annotated locations for NP_990414.1

Status: VALIDATED

Source sequence(s)

JAENSK010000065

UniProtKB/Swiss-Prot

O42422

Conserved Domains (6) summary

cd09548
Location:914 → 983

SAM_EPH-A7; SAM domain of EPH-A7 subfamily of tyrosine kinase receptors

cd10485
Location:30 → 206

EphR_LBD_A7; Ligand Binding Domain of Ephrin type-A Receptor 7

cd00063
Location:443 → 534

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd05066
Location:623 → 889

PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors

pfam00041
Location:333 → 427

fn3; Fibronectin type III domain

pfam14575
Location:562 → 623

EphA2_TM; Ephrin type-A receptor 2 transmembrane domain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

73598654..73758206

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_040696845.2 → XP_040552779.1 ephrin type-A receptor 7 isoform X1

UniProtKB/TrEMBL

A0A8V0XBZ6

Related

ENSGALP00010005650.1, ENSGALT00010009624.1

Conserved Domains (4) summary

cd10485
Location:30 → 206

EphR_LBD_A7; Ligand Binding Domain of Ephrin type-A Receptor 7

cd00063
Location:443 → 534

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd05066
Location:623 → 889

PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors

cl15755
Location:914 → 956

SAM_superfamily; SAM (Sterile alpha motif )
XM_040696846.2 → XP_040552780.1 ephrin type-A receptor 7 isoform X2

Conserved Domains (4) summary

cd10485
Location:30 → 206

EphR_LBD_A7; Ligand Binding Domain of Ephrin type-A Receptor 7

cd00063
Location:443 → 534

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd05066
Location:619 → 885

PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors

cl15755
Location:910 → 952

SAM_superfamily; SAM (Sterile alpha motif )
XM_040696849.2 → XP_040552783.1 ephrin type-A receptor 7 isoform X3

Conserved Domains (4) summary

cd00063
Location:328 → 419

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd05066
Location:508 → 774

PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors

cl02704
Location:30 → 72

EphR_LBD; Ligand Binding Domain of Ephrin Receptors

cl15755
Location:799 → 841

SAM_superfamily; SAM (Sterile alpha motif )
XM_040696850.2 → XP_040552784.1 ephrin type-A receptor 7 isoform X4

Conserved Domains (2) summary

cd00063
Location:332 → 438

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cl02704
Location:30 → 206

EphR_LBD; Ligand Binding Domain of Ephrin Receptors