rigi RNA sensor RIG-I [Salmo salar (Atlantic salmon)] - Gene

Summary

Gene symbol: rigi
Gene description: RNA sensor RIG-I
See related: Ensembl:ENSSSAG00000119673
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Salmo salar
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes; Salmonidae; Salmoninae; Salmo
Also known as: ddx58; rig-i
Orthologs: human zebrafish all
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Genomic context

Location:: chromosome: Un

Exon count:: 22

Annotation release	Status	Assembly	Chr	Location
102	current	Ssal_v3.1 (GCF_905237065.1)	Unplaced Scaffold	NW_025550412.1 (172913..213552)
100	previous assembly	ICSASG_v2 (GCF_000233375.1)	ssa18	NC_027317.1 (70356478..70372550)
100	previous assembly	ICSASG_v2 (GCF_000233375.1)	Unplaced Scaffold	NW_012344123.1 (3168..17491)

NW_025550412.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables double-stranded RNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables single-stranded RNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: probable ATP-dependent RNA helicase DDX58

Names: DEAD (Asp-Glu-Ala-Asp) box polypeptide 58; DExD/H-box helicase 58; retinoic acid-inducible gene-I

NP_001157171.1

EC 3.6.4.13

XP_045569699.1

EC 3.6.4.13

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001163699.1 → NP_001157171.1 probable ATP-dependent RNA helicase DDX58

See identical proteins and their annotated locations for NP_001157171.1

Status: PROVISIONAL

Source sequence(s)

FN178459

UniProtKB/TrEMBL

C7C1L7

Conserved Domains (7) summary

COG1111
Location:269 → 800

MPH1; ERCC4-related helicase [Replication, recombination and repair]

cd00046
Location:283 → 437

DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.

cd08816
Location:2 → 91

CARD_RIG-I_r1; Caspase activation and recruitment domain found in RIG-I, first repeat

cd08817
Location:99 → 190

CARD_RIG-I_r2; Caspase activation and recruitment domain found in RIG-I, second repeat

cd15805
Location:835 → 946

RIG-I_C; C-terminal domain of Retinoic acid-inducible gene (RIG)-I protein, a cytoplasmic viral RNA receptor

cd12090
Location:496 → 627

MDA5_ID; Insert domain of MDA5

pfam00271
Location:636 → 763

Helicase_C; Helicase conserved C-terminal domain