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    Pcnx1 pecanex 1 [ Mus musculus (house mouse) ]

    Gene ID: 54604, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Pcnx1provided by MGI
    Official Full Name
    pecanex 1provided by MGI
    Primary source
    MGI:MGI:1891924
    See related
    Ensembl:ENSMUSG00000021140 AllianceGenome:MGI:1891924
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Pcnx; Pcnxl1; 2900024E21Rik; 3526401J03Rik
    Summary
    Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in cerebral cortex marginal layer; lateral ventricle choroid plexus; medulla oblongata basal plate mantle layer; and metencephalon part of 4th ventricle choroid plexus. Orthologous to human PCNX1 (pecanex 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in lung adult (RPKM 13.9), ovary adult (RPKM 11.9) and 26 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    12 D1; 12 37.98 cM
    Exon count:
    36
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (81906688..82047698)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (81859913..82000924)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene mitogen-activated protein kinase kinase kinase 9 Neighboring gene STARR-positive B cell enhancer ABC_E4034 Neighboring gene STARR-seq mESC enhancer starr_32680 Neighboring gene CapStarr-seq enhancer MGSCv37_chr12:82893600-82893709 Neighboring gene STARR-seq mESC enhancer starr_32681 Neighboring gene predicted gene, 30706 Neighboring gene CapStarr-seq enhancer MGSCv37_chr12:83072406-83072559 Neighboring gene STARR-seq mESC enhancer starr_32682 Neighboring gene predicted gene, 30799 Neighboring gene STARR-seq mESC enhancer starr_32683 Neighboring gene STARR-positive B cell enhancer ABC_E7158 Neighboring gene signal-induced proliferation-associated 1 like 1 Neighboring gene STARR-positive B cell enhancer ABC_E4035 Neighboring gene STARR-positive B cell enhancer ABC_E11517 Neighboring gene predicted gene, 30916

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Corticothalamic Projection Neuron Development beyond Subtype Specification: Fog2 and Intersectional Controls Regulate Intraclass Neuronal Diversity. Galazo MJ, et al. Neuron, 2016 Jul 6. PMID 27321927, Free PMC Article
    2. Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray. Nishimura M, et al. DNA Res, 2004 Oct 31. PMID 15747579
    3. Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2003 Aug 31. PMID 14621295
    4. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
    5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    pecanex-like protein 1
    Names
    pecanex homolog protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_018814.3 → NP_061284.2  pecanex-like protein 1

      See identical proteins and their annotated locations for NP_061284.2

      Status: VALIDATED

      Source sequence(s)
      AC124484, AK129221, BP753289, CF182434, CF746564, CJ107156, CN535767
      Consensus CDS
      CCDS26025.1
      UniProtKB/Swiss-Prot
      Q6ZQ41, Q9CUU7, Q9QYC1
      Related
      ENSMUSP00000021567.6, ENSMUST00000021567.6
      Conserved Domains (4) summary
      COG1266
      Location:993 → 1229
      YdiL; Membrane protease YdiL, CAAX protease family [Posttranslational modification, protein turnover, chaperones]
      pfam05041
      Location:1785 → 2009
      Pecanex_C; Pecanex protein (C-terminus)
      pfam12730
      Location:1035 → 1282
      ABC2_membrane_4; ABC-2 family transporter protein
      cl11542
      Location:1402 → 1527
      EcsB; Bacterial ABC transporter protein EcsB

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      81906688..82047698
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006516090.4 → XP_006516153.1  pecanex-like protein 1 isoform X2

      Conserved Domains (3) summary
      PHA03307
      Location:330 → 616
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam05041
      Location:1780 → 2006
      Pecanex_C; Pecanex protein (C-terminus)
      cl11542
      Location:1397 → 1522
      EcsB; Bacterial ABC transporter protein EcsB

    2. XM_006516089.4 → XP_006516152.1  pecanex-like protein 1 isoform X1

      Conserved Domains (3) summary
      PHA03307
      Location:330 → 616
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam05041
      Location:1784 → 2010
      Pecanex_C; Pecanex protein (C-terminus)
      cl11542
      Location:1401 → 1526
      EcsB; Bacterial ABC transporter protein EcsB

    3. XM_006516091.4 → XP_006516154.1  pecanex-like protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A1Y7VKR5
      Related
      ENSMUSP00000152104.2, ENSMUST00000221721.2
      Conserved Domains (3) summary
      PHA03307
      Location:330 → 616
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam05041
      Location:1779 → 2005
      Pecanex_C; Pecanex protein (C-terminus)
      cl11542
      Location:1396 → 1521
      EcsB; Bacterial ABC transporter protein EcsB

    4. XM_006516092.4 → XP_006516155.1  pecanex-like protein 1 isoform X4

      Conserved Domains (3) summary
      PHA03307
      Location:330 → 616
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam05041
      Location:1679 → 1905
      Pecanex_C; Pecanex protein (C-terminus)
      cl11542
      Location:1296 → 1421
      EcsB; Bacterial ABC transporter protein EcsB

    5. XM_006516093.4 → XP_006516156.1  pecanex-like protein 1 isoform X5

      Conserved Domains (3) summary
      PHA03307
      Location:330 → 616
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam05041
      Location:1674 → 1900
      Pecanex_C; Pecanex protein (C-terminus)
      cl11542
      Location:1291 → 1416
      EcsB; Bacterial ABC transporter protein EcsB

    6. XM_030246823.2 → XP_030102683.1  pecanex-like protein 1 isoform X6

      Conserved Domains (2) summary
      PHA03307
      Location:5 → 138
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam05041
      Location:1307 → 1533
      Pecanex_C; Pecanex protein (C-terminus)

    7. XM_006516095.4 → XP_006516158.1  pecanex-like protein 1 isoform X8

      See identical proteins and their annotated locations for XP_006516158.1

      UniProtKB/TrEMBL
      Q6PG01
      Conserved Domains (1) summary
      pfam05041
      Location:887 → 1113
      Pecanex_C; Pecanex protein (C-terminus)

    8. XM_036157537.1 → XP_036013430.1  pecanex-like protein 1 isoform X8

      UniProtKB/TrEMBL
      Q6PG01
      Conserved Domains (1) summary
      pfam05041
      Location:887 → 1113
      Pecanex_C; Pecanex protein (C-terminus)

    9. XM_017315138.3 → XP_017170627.1  pecanex-like protein 1 isoform X9

      UniProtKB/TrEMBL
      Q3TD89
      Conserved Domains (1) summary
      pfam05041
      Location:642 → 868
      Pecanex_C; Pecanex protein (C-terminus)

    10. XM_006516094.4 → XP_006516157.1  pecanex-like protein 1 isoform X7

      UniProtKB/TrEMBL
      Q6PG01
      Conserved Domains (1) summary
      pfam05041
      Location:892 → 1118
      Pecanex_C; Pecanex protein (C-terminus)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9QYC1.3 GenPept UniProtKB/Swiss-Prot:Q9QYC1

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